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Update faq.md
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stephan-fuchs authored Sep 2, 2023
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Expand Up @@ -49,8 +49,8 @@ In rare cases, the anchor base itself might be mutated, leading to scenarios lik

**Example:**
```plaintex
Reference Sequence: ATGCCATGATT-----AGGAATTCTGA
Sequence with Insertion: ATGCCATGATAGTTTAAGGAATTCTGA
Reference Sequence: ATGCCATGATT-----AGGAATTCTGA
Sequence with SNP preceding Insertion: ATGCCATGATAGTTTAAGGAATTCTGA
```

In such cases, covSonar2 addresses the complexity more explicitly. While covSonar used to express this as a single mutation (`T11AGTTTA`), which might not accurately represent both independent mutation events, covSonar2 dissects the mutations into separate notations. This approach references both independent mutational events as `T11A` and `T11TGTTTA` in the genomic profile. This distinction also ensures accurate matching and interpretation of the mutations independently from each other.
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