lems-emt-pdl1-models-figures

Models and code to generate figures for “Tumor-Mediated Immunosuppression and Cytokine Spreading Affects the Relation Between EMT and PD-L1 Status”. Frontiers in Immunology. doi: 10.3389/fimmu.2023.1219669

Usage

Models

COPASI and Morpheus models can be found in models/copasi_models and models/morpheus_models, respectively.

Figures

Figures are generated reproducibly in R using renv:

1. Download/clone this repository

2. Open the project file (.Rproj) in RStudio

3. Run

   renv::restore()

   to install R package dependencies.

4. Open code.Rmd and choose Run > Run All. Figures will appear in the output folder.

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