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Deep Learning-Based Ranking Method for Subgroup and Predictive Biomarkers Identification

Overview

DeepRAB is a deep learning-based framework designed for identifying subgroups and predictive biomarkers in precision medicine.

Features

  • DeepRAB Framework: Implements the core DeepRAB model for identifying subgroups and predictive biomarkers.
  • Causal Forest Framework: Integrates the Causal Forest (CF) model for estimating conditional average treatment effects (CATE) as a comparison.
  • XGBoost with Modified Loss Function: A customized version of XGBoost tailored for biomarker identification, incorporating an A-learning loss function.
  • Linear Regression Models: Implements linear regression with both modified outcomes and modified covariates.

Installation

Prerequisites

Ensure you have the following installed:

  • Python 3.7+
  • R 4.0+

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