SMRT® Analysis is a powerful, open-source bioinformatics software suite available for analysis of DNA sequencing data from Pacific Biosciences’ SMRT technology.
Users can choose from a variety of analysis protocols that utilize PacBio® and third-party tools. Analysis protocols include de novo genome assembly, cDNA mapping, DNA base-modification detection, and long-amplicon analysis to determine phased consensus sequences.
The browser-based SMRT Portal GUI offers push-button analysis, allowing the user to create, submit, and monitor analysis jobs. The underlying algorithms can be accessed on the command-line for pipeline development with SMRT Pipe, utilizing LIMS-friendly APIs and a large collection of utilities for working with PacBio bas.h5 files and other common file formats. SMRT View is an application for graphical visualization of processed and annotated sequence data, including kinetics data unique to PacBio SMRT technology.
SMRT Analysis can run in single, distributed, or mixed modes. An Amazon Web Service (AWS) cloud-based implementation is available.
PacBio Developer's Network Website
Visit PacBio DevNet for the most up-to-date downloads, documentation and more.
Support for PacBio customers is available through the Customer Portal.
For customers of PacBio Sequencing Providers.