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LLM_SVs

Semantic Labeling of Structural Variants using LLM

Structural variants

Deletions : Loss of a segment of DNA
Duplications: Repeated segments of DNA
Inversions: Reversal of segment of DNA
Translocations: Movement of DNA segments between non-homologous chromosomes
Insertions: Addition of foreign DNA segments

Potential Workflow

Input: A VCF file with structural variant calls
Processing: Extract relevant information (type, location, impact)
LLM interaction: Pass the extracted information to the LLM to generate descriptions and labels
Output: Annotated SV data with semantic descriptions, classification and potential implications

Step1

Step2

Contributors:

1) Ramanandan Prabhakaran
2) Karolis
3) Veena Ghorakvai
4) Anika Pal

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