Python, Dialogflow, Twilio, Whatsapp Chatbot Create Python Virtual Environment Create a virtual environment Give any name you want instead of chatbot_env python -m venv chatbot_env Activate virtual environment Linux, Mac OS source chatbot_env/bin/activate Windows chatbot_env\Scripts\activate Installing requirements from requirements.txt file pip install -r requirements.txt To configure Dialogflow api with flask follow this post To configure Twilio api with Whatsapp follow this post