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Update loadDrugMechDB.py to include treats edges for indication paths #264

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@beasleyjonm beasleyjonm commented Oct 25, 2024

Each indication path in drugmechdb describes the COP for a drug-disease indication pair, but the "treats" edge is not explicitly included. I edited the parser to introduce these as "biolink:treats" edges.

@eKathleenCarter eKathleenCarter linked an issue Oct 28, 2024 that may be closed by this pull request
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Looks like this needs a refactor.

@eKathleenCarter eKathleenCarter added the refactor Parser needs refactoring and revision label Oct 28, 2024
@eKathleenCarter eKathleenCarter self-assigned this Oct 28, 2024
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Given the "treats"/"ameliorates" edge refactor, I hesitate to approve this PR. I suggest we look at it more before merging it into main.

@eKathleenCarter eKathleenCarter added the Biological Context QC Require validation of biological context to ensure accuracy and consistency label Oct 28, 2024
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From the DrugMechDB paper: "DrugMechDB was constructed considering drug-disease indications from the DrugCentral
database, using the version downloaded on September 18, 2020"

So each drug-disease pair in each path in the source file could be considered an indication, at least as of 2020.

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code improvement for DrugMechDB
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