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CTD bug susceptibility != response? #141

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cbizon opened this issue Dec 2, 2022 · 1 comment
Open

CTD bug susceptibility != response? #141

cbizon opened this issue Dec 2, 2022 · 1 comment
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@cbizon
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cbizon commented Dec 2, 2022

http://ctdbase.org/query.go?type=ixn&chemqt=equals&chem=&actionDegreeTypes=increases&actionDegreeTypes=decreases&actionDegreeTypes=affects&actionTypes=response+to+substance&geneqt=equals&gene=GSTP1&pathwayqt=equals&pathway=&taxonqt=equals&taxon=&goqt=equals&go=&sort=chemNmSort&perPage=500&action=Search

The relationship between GSTP1 and Tobacco smoke is: Tobacco Smoke Pollution results in increased susceptibility to GSTP1 protein polymorphism.

ROBOKOPKG currently has this (in prod) as increases_response_to. Can this be updated, maybe with qualifiers?

@cbizon
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cbizon commented Dec 2, 2022

In dev, there is are two edges supposedly from CTD:
One qualified (increases localization of)
One not (increases response to)

I'm not sure that either of these is right...

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