diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index a6795bb06b..5bf53f13b7 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -80,10 +80,10 @@ jobs:
         shell: bash
       # v1 should be the earliest supported version, and v4 the latest.  Tests are only run on v1 and v4.
         run: |
-          echo "python_v1=3.9" >> $GITHUB_ENV
-          echo "python_v2=3.10" >> $GITHUB_ENV
-          echo "python_v3=3.11" >> $GITHUB_ENV
-          echo "python_v4=3.12" >> $GITHUB_ENV
+          echo "python_v1=3.10" >> $GITHUB_ENV
+          echo "python_v2=3.11" >> $GITHUB_ENV
+          echo "python_v3=3.12" >> $GITHUB_ENV
+          echo "python_v4=3.13" >> $GITHUB_ENV
           echo "python_v1_name=v1" >> $GITHUB_ENV
           echo "python_v2_name=v2" >> $GITHUB_ENV
           echo "python_v3_name=v3" >> $GITHUB_ENV
@@ -99,7 +99,7 @@ jobs:
 
       - name: Setup Python for non-Manylinux platforms
         if: matrix.platform.build_python == 'ON' && matrix.platform.os_type != 'manylinux'
-        uses: actions/setup-python@v4
+        uses: actions/setup-python@v5
         id: four_pythons
         with:
           python-version: |
@@ -214,7 +214,7 @@ jobs:
 
       - name: Set MSVC as the default compiler on Windows
         if: matrix.platform.os_type == 'windows'
-        uses: ilammy/msvc-dev-cmd@v1.12.1
+        uses: ilammy/msvc-dev-cmd@v1
 
       - name: Upgrade gcc on Linux
         if: matrix.platform.os_type == 'manylinux'
@@ -446,7 +446,7 @@ jobs:
           echo "artifacts_path=${RUNNER_WORKSPACE}/install-roadrunner" >> $GITHUB_ENV
 
       - name: Upload roadrunner binaries
-        uses: actions/upload-artifact@v3
+        uses: actions/upload-artifact@v4
         with:
           name: ${{ env.artifacts_name }}
           path: ${{ env.artifacts_path }}
@@ -587,7 +587,7 @@ jobs:
 
       - name: Upload RoadRunner Python wheel artifacts
         if: matrix.platform.build_type == 'Release' && matrix.platform.build_python == 'ON'
-        uses: actions/upload-artifact@v3
+        uses: actions/upload-artifact@v4
         with:
           name: ${{ env.roadrunner_python_wheel_artifacts_name }}
           path: ${{ env.roadrunner_python_wheel_artifacts_file }}
diff --git a/requirements.txt b/requirements.txt
index 210ba6aec0..9cbf1e39cc 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1 +1 @@
-numpy~=1.26
+numpy~=2.1
diff --git a/wrappers/Python/roadrunner/PyEventListener.h b/wrappers/Python/roadrunner/PyEventListener.h
index e341c1af82..3d02fbd919 100644
--- a/wrappers/Python/roadrunner/PyEventListener.h
+++ b/wrappers/Python/roadrunner/PyEventListener.h
@@ -117,7 +117,7 @@ class PyEventListener : public EventListener
             */
 
             PyObject *args = Py_BuildValue("(N, i, s)", pyModel, index, eventId.c_str());
-            PyObject *pyres = PyEval_CallObject(pyOnTrigger, args);
+            PyObject *pyres = PyObject_Call(pyOnTrigger, args, NULL);
 
 
             if (PyErr_Occurred()) {
@@ -170,7 +170,7 @@ class PyEventListener : public EventListener
 
             PyObject *pyModel = ExecutableModel_NewPythonObj(model);
             PyObject *args = Py_BuildValue("(N, i, s)", pyModel, index, eventId.c_str());
-            PyObject *pyres = PyEval_CallObject(pyOnAssignment, args);
+            PyObject *pyres = PyObject_Call(pyOnAssignment, args, NULL);
 
             if (PyErr_Occurred()) {
 
diff --git a/wrappers/Python/roadrunner/PyIntegratorListener.h b/wrappers/Python/roadrunner/PyIntegratorListener.h
index 035d74916f..8825c184d9 100644
--- a/wrappers/Python/roadrunner/PyIntegratorListener.h
+++ b/wrappers/Python/roadrunner/PyIntegratorListener.h
@@ -109,7 +109,7 @@ class PyIntegratorListener : public IntegratorListener
             */
 
             PyObject *args = Py_BuildValue("(N, N, d)", pyIntegrator, pyModel, time);
-            PyObject *pyres = PyEval_CallObject(pyOnTimeStep, args);
+            PyObject *pyres = PyObject_Call(pyOnTimeStep, args, NULL);
 
             if (PyErr_Occurred()) {
 
@@ -168,7 +168,7 @@ class PyIntegratorListener : public IntegratorListener
             PyObject *pyIntegrator = Integrator_NewPythonObj(integrator);
             PyObject *pyModel = ExecutableModel_NewPythonObj(model);
             PyObject *args = Py_BuildValue("(N, N, s)", pyIntegrator, pyModel, time);
-            PyObject *pyres = PyEval_CallObject(pyOnEvent, args);
+            PyObject *pyres = PyObject_Call(pyOnEvent, args, NULL);
 
             if (PyErr_Occurred()) {