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simr.owl
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simr.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/simr.owl#"
xml:base="http://purl.obolibrary.org/obo/simr.owl"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:obo="http://purl.obolibrary.org/obo/">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/simr.owl">
<owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/simr/releases/2017-07-28/simr.owl"/>
<rdfs:comment>SIMR Ontology</rdfs:comment>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
<rdfs:label>definition</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#created_by -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
<!-- http://www.geneontology.org/formats/oboInOwl#creation_date -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasDbXref -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasExactSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasOBONamespace -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasSynonymType -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasSynonymType"/>
<!-- http://www.geneontology.org/formats/oboInOwl#id -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
<!-- http://www.geneontology.org/formats/oboInOwl#inSubset -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/SIMR_00000000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_00000000">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<obo:IAO_0000115>Stowers Institute for Medical Research</obo:IAO_0000115>
<rdfs:label xml:lang="en">simr</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SIMR_0000001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000016"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">an example of a class or group.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMRbase_terms</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000001</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">representative</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000001"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">an example of a class or group.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://www.merriam-webster.com/dictionary/representative</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/SIMR_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000016"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">one that is treated or regarded with special favor or liking.</obo:IAO_0000115>
<oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMRbase_terms</oboInOwl:hasOBONamespace>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000002</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">favorite</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000002"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">one that is treated or regarded with special favor or liking.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://www.merriam-webster.com/dictionary/favorite</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/SIMR_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000003">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">media are audo/visual/audiovisual modes of communicating information for mass consumption.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sofia Robb</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2017-06-09T21:13:54Z</oboInOwl:creation_date>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000003</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">media</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000003"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">media are audo/visual/audiovisual modes of communicating information for mass consumption.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIO:001194</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/SIMR_0000004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000003"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A movie is a series of images that are displayed in rapid succession to give the impression of movement.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sofia Robb</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2017-06-09T21:23:40Z</oboInOwl:creation_date>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000004</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">movie</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000004"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A movie is a series of images that are displayed in rapid succession to give the impression of movement.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIO:000297</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/SIMR_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000007"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A figure with a single image.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sofia Robb</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2017-06-09T21:29:09Z</oboInOwl:creation_date>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000006</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">single image</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SIMR_0000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000003"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An image is an affine projection of a visual entity to a two dimensional surface.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sofia Robb</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2017-06-09T21:29:37Z</oboInOwl:creation_date>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000007</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">image</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000007"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An image is an affine projection of a visual entity to a two dimensional surface.</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIO:000081</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/SIMR_0000008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000007"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A figure comprised of multiple images.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sofia Robb</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2017-06-09T21:29:49Z</oboInOwl:creation_date>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000008</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">panel of images</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/SIMR_0000009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000014"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections.</obo:IAO_0000115>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAS:1404-04-2</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:7507</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DrugBank:DB00994</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KEGG:C00384</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KEGG:D08260</oboInOwl:hasDbXref>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Neomycin</oboInOwl:hasExactSynonym>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000009</oboInOwl:id>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#3_STAR"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">neomycin</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000009"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAS:1404-04-2</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KEGG COMPOUND</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000009"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Neomycin</owl:annotatedTarget>
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</owl:Axiom>
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<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1.</obo:IAO_0000115>
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<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SU 5402</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SU-5402</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Su-5402</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">[H]C(c1[nH]cc(C)c1CCC(O)=O)=C1C(=O)Nc2ccccc12</oboInOwl:hasRelatedSynonym>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000011</oboInOwl:id>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#3_STAR"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SU5402</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reaxys:8004406</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reaxys</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-{4-methyl-2-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IUPAC</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#IUPAC_NAME"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#CHARGE"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">296.116</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#MONOISOTOPIC_MASS"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">296.32050</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#MASS"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-[3-(2-carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SUBMITTER</oboInOwl:hasDbXref>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-{[3-(2-carboxyethyl)-4-methylpyrrol-2-yl]methylene}-2-indolinone</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C17H16N2O3</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#FORMULA"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#InChI"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">JNDVEAXZWJIOKB-UHFFFAOYSA-N</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#InChIKey"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SU 5402</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SU-5402</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Su-5402</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000011"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">[H]C(c1[nH]cc(C)c1CCC(O)=O)=C1C(=O)Nc2ccccc12</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#SMILES"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/SIMR_0000012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/SIMR_0000012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000014"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N(3) is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor.</obo:IAO_0000115>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAS:219580-11-7</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:63448</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LINCS:LSM-1026</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:14598292</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:14715624</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:14960493</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:16448042</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:17356708</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19340397</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19903855</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19955487</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reaxys:10130688</oboInOwl:hasDbXref>
<oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1-tert-butyl-3-[2-{[4-(diethylamino)butyl]amino}-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea</oboInOwl:hasExactSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">523.327</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">523.67020</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C28H41N7O3</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CCN(CC)CCCCNc1ncc2cc(-c3cc(OC)cc(OC)c3)c(NC(=O)NC(C)(C)C)nc2n1</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DXCUKNQANPLTEJ-UHFFFAOYSA-N</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PD 173074</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PD-173074</oboInOwl:hasRelatedSynonym>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SIMR:0000012</oboInOwl:id>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#3_STAR"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PD173074</rdfs:label>
</owl:Class>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAS:219580-11-7</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChemIDplus</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:14598292</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:14715624</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:14960493</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:16448042</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:17356708</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19340397</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19903855</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:19955487</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Europe PMC</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reaxys:10130688</owl:annotatedTarget>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reaxys</rdfs:label>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1-tert-butyl-3-[2-{[4-(diethylamino)butyl]amino}-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IUPAC</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#IUPAC_NAME"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#CHARGE"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">523.327</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#MONOISOTOPIC_MASS"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">523.67020</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#MASS"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C28H41N7O3</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#FORMULA"/>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/SIMR_0000012"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
<owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CCN(CC)CCCCNc1ncc2cc(-c3cc(OC)cc(OC)c3)c(NC(=O)NC(C)(C)C)nc2n1</owl:annotatedTarget>
<oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ChEBI</oboInOwl:hasDbXref>
<oboInOwl:hasSynonymType rdf:resource="http://purl.obolibrary.org/obo/SIMR_terms#SMILES"/>
</owl:Axiom>
<owl:Axiom>
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<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
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<obo:IAO_0000115>characteristic of or belonging to reality as perceived rather than as independent of mind</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sofia Robb</oboInOwl:created_by>
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<!-- Generated by the OWL API (version 4.2.6) https://github.com/owlcs/owlapi -->