diff --git a/CHANGES.rst b/CHANGES.rst
index 1bb87ddd0c..004db01f16 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -43,6 +43,8 @@ Bug Fixes
 Cubeviz
 ^^^^^^^
 
+- Fixed copious warnings from spaxel tool when data has INF. [#3368]
+
 Imviz
 ^^^^^
 
diff --git a/jdaviz/configs/cubeviz/plugins/parsers.py b/jdaviz/configs/cubeviz/plugins/parsers.py
index 715df19f4d..017cde1264 100644
--- a/jdaviz/configs/cubeviz/plugins/parsers.py
+++ b/jdaviz/configs/cubeviz/plugins/parsers.py
@@ -456,6 +456,7 @@ def _parse_spectrum1d_3d(app, file_obj, data_label=None,
             flux = val << u.dimensionless_unscaled  # DQ flags have no unit
         elif attr == "uncertainty":
             flux = val.represent_as(StdDevUncertainty).quantity
+            flux[np.isinf(flux)] = np.nan  # Avoid INF from IVAR conversion
         else:
             flux = val
 
diff --git a/jdaviz/configs/cubeviz/plugins/tools.py b/jdaviz/configs/cubeviz/plugins/tools.py
index d49660ba9c..ec77106dda 100644
--- a/jdaviz/configs/cubeviz/plugins/tools.py
+++ b/jdaviz/configs/cubeviz/plugins/tools.py
@@ -172,5 +172,8 @@ def _mouse_move_worker(self, x, y):
             self.viewer.start_stream()
             self.viewer.update_sonified_cube(x, y)
 
-            self._profile_viewer.set_limits(
-                y_min=np.nanmin(y_values) * 0.8, y_max=np.nanmax(y_values) * 1.2)
+            # Data might have inf too.
+            new_ymin = np.nanmin(y_values)
+            new_ymax = np.nanmax(y_values)
+            if np.all(np.isfinite([new_ymin, new_ymax])):
+                self._profile_viewer.set_limits(y_min=new_ymin * 0.8, y_max=new_ymax * 1.2)