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simulate_genotype_call_dataset creates duplicate alleles #1221

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hyanwong opened this issue Jun 7, 2024 · 0 comments
Open

simulate_genotype_call_dataset creates duplicate alleles #1221

hyanwong opened this issue Jun 7, 2024 · 0 comments
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@hyanwong
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hyanwong commented Jun 7, 2024

E.g. we can get 2 "C" values in ds['variant_allele']:

import sgkit as sg
import numpy as np

ds = sg.simulate_genotype_call_dataset(n_variant=10, n_sample=4, missing_pct=0, phased=True, seed=1)
for i, alleles in enumerate(ds['variant_allele'].values):
    print(f"Site {i}: {alleles}")
    assert len(np.unique(alleles)) == len(alleles)

Fails on site 6:

Site 6: [b'T' b'T']
---------------------------------------------------------------------------
AssertionError

This can cause much confusion in downstream analysis. See tskit-dev/tsinfer#927

@hyanwong hyanwong changed the title simulate_genotype_call_dataset created duplicate alleles simulate_genotype_call_dataset creates duplicate alleles Jun 7, 2024
@jeromekelleher jeromekelleher added the bug Something isn't working label Jun 7, 2024
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