Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.

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78 repositories

wpgsd
Public
Weighted parametric group sequential design
R
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GNU General Public License v3.0
•2•1•3•0•Updated Jan 15, 2025Jan 15, 2025
simtrial
Public
Clinical trial simulation for time-to-event endpoints
R
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GNU General Public License v3.0
•8•19•7•1•Updated Jan 15, 2025Jan 15, 2025
metalite.sl
Public
An R package designed for the analysis & reporting of subject baseline characteristics in clinical trials.
R
•
GNU General Public License v3.0
•1•0•17•1•Updated Jan 14, 2025Jan 14, 2025
forestly
Public
Interactive forest plot for adverse events analysis
R
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GNU General Public License v3.0
•3•14•3•1•Updated Jan 9, 2025Jan 9, 2025
gsDesign2
Public
Group Sequential Design Under Non-Proportional Hazards
R
•
GNU General Public License v3.0
•8•22•7•3•Updated Jan 8, 2025Jan 8, 2025
psm3mkv
Public
psm3mkv: A package to evaluate the fit and efficiency of three state oncology cost-effectiveness model structures
R
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GNU General Public License v3.0
•1•9•2•0•Updated Dec 18, 2024Dec 18, 2024
bgc-pipeline
Public
Jupyter Notebook
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MIT License
•1•11•2•0•Updated Dec 10, 2024Dec 10, 2024
CEEDesigns.jl
Public
A decision-making framework for the cost-efficient design of experiments, balancing the value of acquired experimental evidence and incurred costs.
decision-making julia-language experimental-design
Julia
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Other
•1•7•0•0•Updated Nov 22, 2024Nov 22, 2024
metalite.ae
Public
An R package for standard adverse events analysis
metadata clinical-trials cdisc r-package
R
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GNU General Public License v3.0
•4•17•2•0•Updated Nov 19, 2024Nov 19, 2024
pkglite
Public
Compact Package Representations
package clinical-trials packaging-tool ectd pharmaverse r
R
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GNU General Public License v3.0
•4•30•5•0•Updated Nov 9, 2024Nov 9, 2024
r2rtf
Public
Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
R
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GNU General Public License v3.0
•20•78•6•0•Updated Sep 30, 2024Sep 30, 2024
BioPhi
Public
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
antibody oasis humanization sapiens humanness
Python
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MIT License
•46•166•30•0•Updated Sep 16, 2024Sep 16, 2024
metalite
Public
An R package to create metadata structure for ADaM data analysis and reporting
metadata clinical-trials r-package cdisc
R
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GNU General Public License v3.0
•6•15•1•0•Updated Aug 22, 2024Aug 22, 2024
AnNoBrainer
Public archive
0•0•0•0•Updated Aug 7, 2024Aug 7, 2024
puqsar
Public
Python
•
GNU General Public License v3.0
•1•0•0•0•Updated Jul 13, 2024Jul 13, 2024
MolPROP
Public
fuses molecular language and graph representation for property prediction
Python
•2•13•0•0•Updated Jun 1, 2024Jun 1, 2024
boxly
Public
Interactive box plot for clinical trial analysis
R
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GNU General Public License v3.0
•1•13•5•0•Updated May 17, 2024May 17, 2024
ProbeDesign
Public
HTML
•1•1•0•0•Updated May 9, 2024May 9, 2024
mRNAid
Public
Jupyter Notebook
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Other
•13•14•9•0•Updated May 6, 2024May 6, 2024
.github
Public
0•0•0•0•Updated May 1, 2024May 1, 2024
Line-of-Therapy-Algorithm
Public
This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
Python
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GNU General Public License v3.0
•17•28•2•1•Updated Apr 29, 2024Apr 29, 2024
AbLEF
Public
Antibody Langauge Ensemble Fusion - fuses antibody structural ensemble and language representation for property prediction
Python
•2•10•0•0•Updated Apr 23, 2024Apr 23, 2024
ReactiveDynamics.jl
Public
A Julia package that implements a category of reaction (transportation) network-type dynamical systems.
optimization decision-making julia-language reaction-network strategic-planning differential-equations scientific-machine-learning
Julia
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Other
•3•17•1•1•Updated Apr 23, 2024Apr 23, 2024
rdf2x
Public
RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.
json sql linked-data sparql rdf conversion postgresql spark
Java
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Apache License 2.0
•11•48•3•4•Updated Apr 15, 2024Apr 15, 2024
AbPROP
Public
Python
•
Apache License 2.0
•1•4•0•0•Updated Mar 23, 2024Mar 23, 2024
AlgebraicAgents.jl
Public
A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!
julia julia-language dynamical-systems differential-equations stochastic-processes
Julia
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Other
•3•20•0•1•Updated Mar 18, 2024Mar 18, 2024
sonar-r-plugin
Public
Adds support for R language into SonarQube. It uses output from lintr tool which is processed by the plugin and uploaded into SonarQube server.
sonarqube rlanguage
Java
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Apache License 2.0
•19•24•7•2•Updated Mar 4, 2024Mar 4, 2024
simvaxpmx
Public
Elucidating vaccine efficacy using a correlate of protection, demographics, and logistic regression
R
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Other
•1•3•0•0•Updated Feb 29, 2024Feb 29, 2024
matcher
Public
Matcher is a tool for understanding how chemical structure optimization problems have been solved. Matcher enables deep control over searching structure/activity relationships (SAR) derived from large datasets, and takes the form of an accessible web application with simple deployment. Matcher is built around the mmpdb platform.
search-engine chemistry docker-compose web-application drug-discovery search-algorithm
Python
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MIT License
•10•56•0•0•Updated Feb 21, 2024Feb 21, 2024
gMCPLite
Public
Lightweight graph-based multiple comparison procedures
R
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GNU General Public License v3.0
•3•10•0•0•Updated Feb 13, 2024Feb 13, 2024