diff --git a/src/client/repl/nativeRepl.ts b/src/client/repl/nativeRepl.ts
index 9f65df9567fb..e69678d567bc 100644
--- a/src/client/repl/nativeRepl.ts
+++ b/src/client/repl/nativeRepl.ts
@@ -10,13 +10,8 @@ import {
     Uri,
     workspace,
     WorkspaceFolder,
-    window,
-    TabInputNotebook,
-    TabInputTextDiff,
-    TabInputText,
 } from 'vscode';
 import { Disposable } from 'vscode-jsonrpc';
-import * as path from 'path';
 import { PVSC_EXTENSION_ID } from '../common/constants';
 import { showQuickPick } from '../common/vscodeApis/windowApis';
 import { getWorkspaceFolders } from '../common/vscodeApis/workspaceApis';
@@ -28,6 +23,7 @@ import { EventName } from '../telemetry/constants';
 import { sendTelemetryEvent } from '../telemetry';
 import { VariablesProvider } from './variables/variablesProvider';
 import { VariableRequester } from './variables/variableRequester';
+import { getTabNameForUri } from './replUtils';
 
 const NATIVE_REPL_URI_MEMENTO = 'nativeReplUri';
 let nativeRepl: NativeRepl | undefined; // In multi REPL scenario, hashmap of URI to Repl.
@@ -47,8 +43,6 @@ export class NativeRepl implements Disposable {
 
     public newReplSession: boolean | undefined = true;
 
-    private replUri: Uri | undefined;
-
     private context: ExtensionContext;
 
     // TODO: In the future, could also have attribute of URI for file specific REPL.
@@ -82,7 +76,6 @@ export class NativeRepl implements Disposable {
                 if (this.notebookDocument && nb.uri.toString() === this.notebookDocument.uri.toString()) {
                     this.notebookDocument = undefined;
                     this.newReplSession = true;
-                    this.replUri = undefined;
                     await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, undefined);
                 }
             }),
@@ -168,28 +161,20 @@ export class NativeRepl implements Disposable {
         if (mementoUri) {
             const replTabBeforeReload = openNotebookDocuments.find((uri) => uri.fsPath === mementoUri?.fsPath);
             if (replTabBeforeReload) {
-                this.replUri = replTabBeforeReload;
                 this.notebookDocument = workspace.notebookDocuments.find(
                     (doc) => doc.uri.fsPath === replTabBeforeReload.fsPath,
                 );
-                await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, this.replUri.toString());
-                const myFileName = path.basename(this.replUri.fsPath);
-
-                // const tabNames = getOpenTabNames();
-                const tabLabel = getTabNameForUri(this.replUri);
-                if (tabLabel !== 'Python REPL') {
-                    const regex = /^Untitled-\d+\.ipynb$/;
-                    const isUntitled = regex.test(myFileName);
+                await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, replTabBeforeReload.toString());
 
-                    this.replUri = undefined;
+                // If repl URI does not have tabLabel 'Python REPL', something has changed:
+                // e.g. creation of untitled notebook without Python extension knowing.
+                if (getTabNameForUri(replTabBeforeReload) !== 'Python REPL') {
                     mementoUri = undefined;
-
                     await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, undefined);
                     this.notebookDocument = undefined;
                 }
             }
         } else {
-            this.replUri = undefined;
             mementoUri = undefined;
             await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, undefined);
             this.notebookDocument = undefined;
@@ -198,8 +183,7 @@ export class NativeRepl implements Disposable {
         const notebookEditor = await openInteractiveREPL(this.replController, this.notebookDocument, mementoUri);
 
         this.notebookDocument = notebookEditor.notebook;
-        this.replUri = this.notebookDocument.uri;
-        await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, this.replUri.toString());
+        await this.context.globalState.update(NATIVE_REPL_URI_MEMENTO, this.notebookDocument.uri.toString());
 
         if (this.notebookDocument) {
             this.replController.updateNotebookAffinity(this.notebookDocument, NotebookControllerAffinity.Default);
@@ -211,43 +195,6 @@ export class NativeRepl implements Disposable {
     }
 }
 
-function getOpenTabNames(): string[] {
-    const tabNames: string[] = [];
-    const tabGroups = window.tabGroups.all;
-
-    for (const tabGroup of tabGroups) {
-        for (const tab of tabGroup.tabs) {
-            tabNames.push(tab.label);
-        }
-    }
-    // TODO if tabName includes 'Python REPL' and there are other 'Untitled-*.ipynb' then, we need to re-create REPL instance with new URI.
-    return tabNames;
-}
-
-function getTabNameForUri(uri: Uri): string | undefined {
-    const tabGroups = window.tabGroups.all;
-
-    for (const tabGroup of tabGroups) {
-        for (const tab of tabGroup.tabs) {
-            if (tab.input instanceof TabInputText && tab.input.uri.toString() === uri.toString()) {
-                return tab.label;
-            }
-            if (tab.input instanceof TabInputTextDiff) {
-                if (
-                    tab.input.original.toString() === uri.toString() ||
-                    tab.input.modified.toString() === uri.toString()
-                ) {
-                    return tab.label;
-                }
-            } else if (tab.input instanceof TabInputNotebook && tab.input.uri.toString() === uri.toString()) {
-                return tab.label;
-            }
-        }
-    }
-
-    return undefined;
-}
-
 /**
  * Get Singleton Native REPL Instance
  * @param interpreter
diff --git a/src/client/repl/replCommandHandler.ts b/src/client/repl/replCommandHandler.ts
index 6bfd4d87bc8e..97c4364e777d 100644
--- a/src/client/repl/replCommandHandler.ts
+++ b/src/client/repl/replCommandHandler.ts
@@ -26,14 +26,15 @@ export async function openInteractiveREPL(
     let viewColumn = ViewColumn.Beside;
     if (mementoValue) {
         // also check if memento value URI tab has file name of Python REPL
-        // Cachhed NotebookDocument exists.
+        // Cached NotebookDocument exists.
         notebookDocument = await workspace.openNotebookDocument(mementoValue as Uri);
     } else if (notebookDocument) {
         // Case where NotebookDocument (REPL document already exists in the tab)
         const existingReplViewColumn = getExistingReplViewColumn(notebookDocument);
         viewColumn = existingReplViewColumn ?? viewColumn;
     } else if (!notebookDocument) {
-        // Case where NotebookDocument doesnt exist, create a blank one.
+        // Case where NotebookDocument doesnt exist, or
+        // became outdated (untitled.ipynb created without Python extension knowing, effectively taking over original Python REPL's URI)
         notebookDocument = await workspace.openNotebookDocument('jupyter-notebook');
     }
     const editor = window.showNotebookDocument(notebookDocument!, {
diff --git a/src/client/repl/replUtils.ts b/src/client/repl/replUtils.ts
index 5f58f461155b..6f0fd8bc1dee 100644
--- a/src/client/repl/replUtils.ts
+++ b/src/client/repl/replUtils.ts
@@ -99,3 +99,21 @@ export function getExistingReplViewColumn(notebookDocument: NotebookDocument): V
     }
     return undefined;
 }
+/**
+ * Function that will return tab name for before reloading VS Code
+ * This is so we can make sure tab name is still 'Python REPL' after reloading VS Code,
+ * and make sure Python REPL does not get 'merged' into unaware untitled.ipynb tab.
+ */
+export function getTabNameForUri(uri: Uri): string | undefined {
+    const tabGroups = window.tabGroups.all;
+
+    for (const tabGroup of tabGroups) {
+        for (const tab of tabGroup.tabs) {
+            if (tab.input instanceof TabInputNotebook && tab.input.uri.toString() === uri.toString()) {
+                return tab.label;
+            }
+        }
+    }
+
+    return undefined;
+}