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Breakpoint caller should use novel kmers #13

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noporpoise opened this issue Aug 10, 2015 · 0 comments
Open

Breakpoint caller should use novel kmers #13

noporpoise opened this issue Aug 10, 2015 · 0 comments

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@noporpoise
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The breakpoint caller should mark kmers if they are used in a call. Unused kmers that are in a sample and not the referece ("novel kmers") should be used to seed a second breakpoint caller.

The novel kmer breakpoint caller should perform a breadth-first search (BFS) to find the nearest kmer that occurs in the reference either side. The shortest path between these kmers should be reported as a putative breakpoint call. This caller will have a high false positive rate, but may catch a few reasonable SNPs / indels.

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