diff --git a/doxygen/09_ReleaseNotes.dox b/doxygen/09_ReleaseNotes.dox
index fa57cb8233..a606a7d350 100644
--- a/doxygen/09_ReleaseNotes.dox
+++ b/doxygen/09_ReleaseNotes.dox
@@ -1,4 +1,14 @@
 /*! \page ReleaseNotes Release Notes
+Release Notes for GeNN v4.5.1 (PyGeNN 0.4.6)
+====
+This release fixes several small issues found in the 4.5.0 release.
+
+Bug fixes:
+----
+1. Fixed cause of the warnings about memory leaks which were generated when sparse connectivity initialisation snippets were defined in PyGeNN.
+2. Fixed bug in model change detection which resulted in memory usage estimate increasing every time the model subsequently changed.
+3. Fixed several bugs effecting the implementation of custom update models in CUDA and OpenCL.
+
 Release Notes for GeNN v4.5.0 (PyGeNN 0.4.5)
 ====
 This release adds a number of significant new features to GeNN as well as several usability improvements for PyGeNN.
diff --git a/setup.py b/setup.py
index e87122e7da..8086d48ef7 100644
--- a/setup.py
+++ b/setup.py
@@ -178,7 +178,7 @@
                                  **backend_extension_kwargs))
 
 setup(name = "pygenn",
-      version = "0.4.5",
+      version = "0.4.6",
       packages = find_packages(),
       package_data={"pygenn": package_data},
 
diff --git a/version.txt b/version.txt
index a84947d6ff..4404a17bae 100644
--- a/version.txt
+++ b/version.txt
@@ -1 +1 @@
-4.5.0
+4.5.1