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Load from HELM: RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}$$$$V2.0
Create antisense for that chain
Actual behavior
System creates all DNA bases instead of RNA ones in antisense chain.
HELM export result: RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}|RNA2{R(A,C,G,T)P.R(A,C,T)P.R(A,G,T)P.R(A,T)P}$RNA1,RNA2,2:pair-2:pair|RNA1,RNA2,5:pair-5:pair|RNA1,RNA2,8:pair-8:pair|RNA1,RNA2,11:pair-11:pair$$$V2.0
Expected behavior
System creates all RNA bases
HELM export result: RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}|RNA2{R(A,C,G,U)P.R(A,C,U)P.R(A,G,U)P.R(A,U)P}$RNA1,RNA2,2:pair-2:pair|RNA1,RNA2,5:pair-5:pair|RNA1,RNA2,8:pair-8:pair|RNA1,RNA2,11:pair-11:pair$$$V2.0
AlexeyGirin
changed the title
N, D, H, W, Y ambiguous DNA bases wrongly converted to DNA bases on antisense creation
N, D, H, W ambiguous DNA bases wrongly converted to DNA bases on antisense creation
Dec 23, 2024
AlexeyGirin
changed the title
N, D, H, W ambiguous DNA bases wrongly converted to DNA bases on antisense creation
Ambiguous DNA bases (N, D, H, W) wrongly converted to DNA bases on antisense creation
Dec 23, 2024
Steps to Reproduce
RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}$$$$V2.0
Actual behavior
System creates all DNA bases instead of RNA ones in antisense chain.
HELM export result:
RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}|RNA2{R(A,C,G,T)P.R(A,C,T)P.R(A,G,T)P.R(A,T)P}$RNA1,RNA2,2:pair-2:pair|RNA1,RNA2,5:pair-5:pair|RNA1,RNA2,8:pair-8:pair|RNA1,RNA2,11:pair-11:pair$$$V2.0
Expected behavior
System creates all RNA bases
HELM export result:
RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}|RNA2{R(A,C,G,U)P.R(A,C,U)P.R(A,G,U)P.R(A,U)P}$RNA1,RNA2,2:pair-2:pair|RNA1,RNA2,5:pair-5:pair|RNA1,RNA2,8:pair-8:pair|RNA1,RNA2,11:pair-11:pair$$$V2.0
As per requirement:
Complementary bases
Versions
Issue found while testing - #5678
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