diff --git a/.changes/next-release/bugfix-Signing-82847.json b/.changes/next-release/bugfix-Signing-82847.json
new file mode 100644
index 0000000000..11d085e489
--- /dev/null
+++ b/.changes/next-release/bugfix-Signing-82847.json
@@ -0,0 +1,5 @@
+{
+  "type": "bugfix",
+  "category": "Signing",
+  "description": "No longer sign transfer-encoding header for SigV4"
+}
diff --git a/botocore/auth.py b/botocore/auth.py
index 66e605a665..bacbd39dde 100644
--- a/botocore/auth.py
+++ b/botocore/auth.py
@@ -65,6 +65,7 @@
 SIGV4_TIMESTAMP = '%Y%m%dT%H%M%SZ'
 SIGNED_HEADERS_BLACKLIST = [
     'expect',
+    'transfer-encoding',
     'user-agent',
     'x-amzn-trace-id',
 ]
diff --git a/tests/unit/auth/test_signers.py b/tests/unit/auth/test_signers.py
index d1b301e35d..c95d042b04 100644
--- a/tests/unit/auth/test_signers.py
+++ b/tests/unit/auth/test_signers.py
@@ -374,7 +374,7 @@ def test_query_string_params_in_urls(self):
         cqs = self.auth.canonical_query_string(request)
         self.assertEqual('marker=%C3%A4%C3%B6%C3%BC-01.txt&prefix=', cqs)
 
-    def _test_blacklist_header(self, header, value):
+    def _test_blocklist_header(self, header, value):
         request = AWSRequest()
         request.url = 'https://s3.amazonaws.com/bucket/foo'
         request.method = 'PUT'
@@ -386,16 +386,19 @@ def _test_blacklist_header(self, header, value):
         auth.add_auth(request)
         self.assertNotIn(header, request.headers['Authorization'])
 
-    def test_blacklist_expect_headers(self):
-        self._test_blacklist_header('expect', '100-continue')
+    def test_blocklist_expect_headers(self):
+        self._test_blocklist_header('expect', '100-continue')
 
-    def test_blacklist_trace_id(self):
-        self._test_blacklist_header(
+    def test_blocklist_trace_id(self):
+        self._test_blocklist_header(
             'x-amzn-trace-id', 'Root=foo;Parent=bar;Sampleid=1'
         )
 
-    def test_blacklist_headers(self):
-        self._test_blacklist_header('user-agent', 'botocore/1.4.11')
+    def test_blocklist_user_agent_header(self):
+        self._test_blocklist_header('user-agent', 'botocore/1.4.11')
+
+    def test_blocklist_transfer_encoding_header(self):
+        self._test_blocklist_header('transfer-encoding', 'chunked')
 
     def test_uses_sha256_if_config_value_is_true(self):
         self.client_config.s3['payload_signing_enabled'] = True