diff --git a/Orange/widgets/data/oweditdomain.py b/Orange/widgets/data/oweditdomain.py
index 364a1aa30ea..30918cb3322 100644
--- a/Orange/widgets/data/oweditdomain.py
+++ b/Orange/widgets/data/oweditdomain.py
@@ -2837,11 +2837,6 @@ def datetime_to_epoch(dti: pd.DatetimeIndex, only_time) -> np.ndarray:
     # when dti has timezone info also the subtracted timestamp must have it
     # otherwise subtracting fails
     initial_ts = pd.Timestamp("1970-01-01", tz=None if dti.tz is None else "UTC")
-    # pandas in versions before 1.4 don't support subtracting different timezones
-    # remove next two lines when read-the-docs start supporting config files
-    # for subprojects, or they change default python version to 3.8
-    if dti.tz is not None:
-        dti = dti.tz_convert("UTC")
     delta = dti - (dti.normalize() if only_time else initial_ts)
     return (delta / pd.Timedelta("1s")).values
 
diff --git a/Orange/widgets/data/owgroupby.py b/Orange/widgets/data/owgroupby.py
index 6e654df5c12..55d5b02893f 100644
--- a/Orange/widgets/data/owgroupby.py
+++ b/Orange/widgets/data/owgroupby.py
@@ -77,8 +77,6 @@ def var(s):
     """
     if is_datetime64_any_dtype(s):
         initial_ts = pd.Timestamp("1970-01-01", tz=None if s.dt.tz is None else "UTC")
-        if s.dt.tz is not None:
-            s = s.tz_convert("UTC")
         s = (s - initial_ts) / pd.Timedelta("1s")
     var_ = s.var()
     return var_.total_seconds() if isinstance(var_, pd.Timedelta) else var_
diff --git a/Orange/widgets/data/tests/test_oweditdomain.py b/Orange/widgets/data/tests/test_oweditdomain.py
index 0881fed3a7d..6c14ef27908 100644
--- a/Orange/widgets/data/tests/test_oweditdomain.py
+++ b/Orange/widgets/data/tests/test_oweditdomain.py
@@ -957,17 +957,6 @@ def test_as_time(self):
             np.array(list(chain(expected, expected)), dtype=float).transpose()
         )
 
-    def test_raise_pandas_version(self):
-        """
-        When this test start to fail:
-        - remove this test
-        - remove if clause in datetime_to_epoch function and supporting comments
-        - remove same if clause in var function in owgroupby (line 77, 78)
-        - set pandas dependency version to pandas>=1.4
-        """
-        from datetime import datetime
-        self.assertLess(datetime.today(), datetime(2023, 1, 1))
-
     def test_reinterpret_string(self):
         table = self.data_str
         domain = table.domain
diff --git a/requirements-core.txt b/requirements-core.txt
index 1ff6c5ea27e..d1ef618cfe4 100644
--- a/requirements-core.txt
+++ b/requirements-core.txt
@@ -22,7 +22,7 @@ python-louvain>=0.13
 requests
 openTSNE>=0.6.1
 baycomp>=1.0.2
-pandas>=1.3.0,!=1.5.0
+pandas>=1.4.0,!=1.5.0
 pyyaml
 openpyxl
 httpx>=0.21.0
diff --git a/tox.ini b/tox.ini
index ba8dea43c5c..912ce647ac2 100644
--- a/tox.ini
+++ b/tox.ini
@@ -65,7 +65,7 @@ deps =
     # oldest: requests
     oldest: openTSNE==0.6.1
     oldest: baycomp==1.0.2
-    oldest: pandas==1.3.0
+    oldest: pandas==1.4.0
     # oldest: pyyaml
     # oldest: openpyxl
     oldest: httpx==0.21.0