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I have seen similar behaviour with MRI images with either a coronal or sagittal native plane. My guess is that the transformation matrix in the image header is not properly used.
In the newest MITK release MITK-2016-11 the issue is resolved, tested with MITK-Workbench on a set of MRI images.
Hence, the solution would be to use MITK-2016-11 in MITK-GEM. However, this would mean dropping the statistics plugin and help for MacOSx. Other options would be to create separate branches for Win-Linux and MacOSx, rewrite the two plugins, or wait for MITK to resolve the issue.
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