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RosettaMP-LipidAcc.md

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RosettaMP Application: mp_lipid_acc

Code and Demo

The executable can be found in Rosetta/main/source/src/apps/public/membrane/mp_lipid_acc.cc

The application can also be run on the ROSIE server: [http://rosie.rosettacommons.org/mp_lipid_acc]

Description

A full description of the algorithm can be found in

  • Koehler Leman, J., Lyskov, S. & Bonneau, R. Computing structure-based lipid accessibility of membrane proteins with mp_lipid_acc in RosettaMP. BMC Bioinformatics 18, 115 (2017).

A protocol capture with a zip folder of corresponding files is available in the Supplement of this paper.

The implementation is based on RosettaMP:

  • Alford, R. F., Koehler Leman, J., Weitzner, B. D., Duran, A. M., Tilley, D. C., Elazar, A. & Gray, J. J. An Integrated Framework Advancing Membrane Protein Modeling and Design. PLoS Comput. Biol. 11, e1004398 (2015).

Contact

Questions and comments to: