QSAR_Machine_Learning_Model_to_Predict_Bioactivity.ipynb

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            "Collecting rdkit\n",
            "  Downloading rdkit-2024.9.1-cp310-cp310-manylinux_2_28_x86_64.whl.metadata (4.0 kB)\n",
            "Requirement already satisfied: numpy in /usr/local/lib/python3.10/dist-packages (from rdkit) (1.26.4)\n",
            "Requirement already satisfied: Pillow in /usr/local/lib/python3.10/dist-packages (from rdkit) (11.0.0)\n",
            "Downloading rdkit-2024.9.1-cp310-cp310-manylinux_2_28_x86_64.whl (33.3 MB)\n",
            "\u001b[2K   \u001b[90m━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━\u001b[0m \u001b[32m33.3/33.3 MB\u001b[0m \u001b[31m27.7 MB/s\u001b[0m eta \u001b[36m0:00:00\u001b[0m\n",
            "\u001b[?25hInstalling collected packages: rdkit\n",
            "Successfully installed rdkit-2024.9.1\n"
          ]
        }
      ],
      "source": [
        "!pip install rdkit"
      ]
    },
    {
      "cell_type": "code",
      "source": [
        "import pandas as pd\n",
        "import numpy as np\n",
        "from rdkit import Chem\n",
        "from rdkit.Chem import Descriptors\n",
        "from rdkit.Chem import rdMolDescriptors\n",
        "from rdkit.Chem import Descriptors, rdMolDescriptors, AllChem\n",
        "from rdkit.DataStructs import cDataStructs\n",
        "from sklearn.feature_selection import VarianceThreshold\n",
        "from sklearn.model_selection import train_test_split\n",
        "from sklearn.ensemble import RandomForestRegressor"
      ],
      "metadata": {
        "id": "b8PRqLLs_Yqj"
      },
      "execution_count": 2,
      "outputs": []
    },
    {
      "cell_type": "markdown",
      "source": [
        "#**Upload Bioactivity data (pIC50) of molecules (smiles)**"
      ],
      "metadata": {
        "id": "-yofM7AdavI8"
      }
    },
    {
      "cell_type": "code",
      "execution_count": 3,
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        "id": "_11WHIiRTOag",
        "outputId": "d03f7f1f-a4b2-4ca5-e26a-bc4bb2cdbce1"
      },
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
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              "                                                 Smiles     pIC50\n",
              "0     CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn...  5.484537\n",
              "1                  O=C(Nc1ccc(Cl)cc1)c1ccccc1NCc1ccncc1  5.136677\n",
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              "3     COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n...  6.657577\n",
              "4              COc1cc2ncc(N[C@H]3CC[C@H](O)CC3)nc2cc1OC  5.431798\n",
              "...                                                 ...       ...\n",
              "2464                      COc1cc2ncnc(Nc3ccccc3)c2cc1OC  7.537602\n",
              "2465                   COc1cc2ncnc(Nc3cccc(F)c3)c2cc1OC  8.420216\n",
              "2466                  COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1OC  5.864231\n",
              "2467  COc1nccc(-c2c(-c3ccc(F)cc3)ncn2[C@H]2CC[C@H](O...  7.080922\n",
              "2468           COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC  6.428291\n",
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              "summary": "{\n  \"name\": \"df\",\n  \"rows\": 2469,\n  \"fields\": [\n    {\n      \"column\": \"Smiles\",\n      \"properties\": {\n        \"dtype\": \"string\",\n        \"num_unique_values\": 2469,\n        \"samples\": [\n          \"CCN1CCN(Cc2ccc(-c3cc4c(N[C@@H](C)c5ccccc5)ncnc4[nH]3)cc2)CC1\",\n          \"COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCC[C@H]1CC(N)=O\",\n          \"c1ccc(OCc2nnc(Cc3nc4ccccc4[nH]3)o2)cc1\"\n        ],\n        \"semantic_type\": \"\",\n        \"description\": \"\"\n      }\n    },\n    {\n      \"column\": \"pIC50\",\n      \"properties\": {\n        \"dtype\": \"number\",\n        \"std\": 1.4010867389571782,\n        \"min\": 1.602059991,\n        \"max\": 11.22184875,\n        \"num_unique_values\": 1231,\n        \"samples\": [\n          6.665546249,\n          5.665546249,\n          5.619788758\n        ],\n        \"semantic_type\": \"\",\n        \"description\": \"\"\n      }\n    }\n  ]\n}"
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          "metadata": {},
          "execution_count": 3
        }
      ],
      "source": [
        "\n",
        "df = pd.read_csv('Bioactivity_Data_clean.csv')\n",
        "df"
      ]
    },
    {
      "cell_type": "code",
      "source": [
        "df = df.dropna ()\n",
        "df"
      ],
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 424
        },
        "id": "uBPbjwxHR57i",
        "outputId": "0b69e27e-7eed-4a0c-8c97-7603a05c41d1"
      },
      "execution_count": 4,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "                                                 Smiles     pIC50\n",
              "0     CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn...  5.484537\n",
              "1                  O=C(Nc1ccc(Cl)cc1)c1ccccc1NCc1ccncc1  5.136677\n",
              "2                            c1ccc(CNc2ncnc3ccccc23)cc1  6.494850\n",
              "3     COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n...  6.657577\n",
              "4              COc1cc2ncc(N[C@H]3CC[C@H](O)CC3)nc2cc1OC  5.431798\n",
              "...                                                 ...       ...\n",
              "2464                      COc1cc2ncnc(Nc3ccccc3)c2cc1OC  7.537602\n",
              "2465                   COc1cc2ncnc(Nc3cccc(F)c3)c2cc1OC  8.420216\n",
              "2466                  COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1OC  5.864231\n",
              "2467  COc1nccc(-c2c(-c3ccc(F)cc3)ncn2[C@H]2CC[C@H](O...  7.080922\n",
              "2468           COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC  6.428291\n",
              "\n",
              "[2469 rows x 2 columns]"
            ],
            "text/html": [
              "\n",
              "  <div id=\"df-8d4aac0a-bcb6-40ca-9263-5952a0a563ff\" class=\"colab-df-container\">\n",
              "    <div>\n",
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              "        vertical-align: middle;\n",
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              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>Smiles</th>\n",
              "      <th>pIC50</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn...</td>\n",
              "      <td>5.484537</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>O=C(Nc1ccc(Cl)cc1)c1ccccc1NCc1ccncc1</td>\n",
              "      <td>5.136677</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>c1ccc(CNc2ncnc3ccccc23)cc1</td>\n",
              "      <td>6.494850</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n...</td>\n",
              "      <td>6.657577</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>COc1cc2ncc(N[C@H]3CC[C@H](O)CC3)nc2cc1OC</td>\n",
              "      <td>5.431798</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>...</th>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2464</th>\n",
              "      <td>COc1cc2ncnc(Nc3ccccc3)c2cc1OC</td>\n",
              "      <td>7.537602</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2465</th>\n",
              "      <td>COc1cc2ncnc(Nc3cccc(F)c3)c2cc1OC</td>\n",
              "      <td>8.420216</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2466</th>\n",
              "      <td>COc1ccc2ncnc(Nc3cccc(Br)c3)c2c1OC</td>\n",
              "      <td>5.864231</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2467</th>\n",
              "      <td>COc1nccc(-c2c(-c3ccc(F)cc3)ncn2[C@H]2CC[C@H](O...</td>\n",
              "      <td>7.080922</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2468</th>\n",
              "      <td>COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC</td>\n",
              "      <td>6.428291</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>2469 rows × 2 columns</p>\n",
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              "          await google.colab.kernel.invokeFunction('convertToInteractive',\n",
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              "\n",
              "        const docLinkHtml = 'Like what you see? Visit the ' +\n",
              "          '<a target=\"_blank\" href=https://colab.research.google.com/notebooks/data_table.ipynb>data table notebook</a>'\n",
              "          + ' to learn more about interactive tables.';\n",
              "        element.innerHTML = '';\n",
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              "  .colab-df-quickchart-complete:disabled,\n",
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              "  }\n",
              "\n",
              "  .colab-df-spinner {\n",
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              "    animation:\n",
              "      spin 1s steps(1) infinite;\n",
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              "\n",
              "  @keyframes spin {\n",
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              "      border-right-color: var(--fill-color);\n",
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              "      border-color: transparent;\n",
              "      border-right-color: var(--fill-color);\n",
              "      border-bottom-color: var(--fill-color);\n",
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              "      border-bottom-color: var(--fill-color);\n",
              "    }\n",
              "  }\n",
              "</style>\n",
              "\n",
              "  <script>\n",
              "    async function quickchart(key) {\n",
              "      const quickchartButtonEl =\n",
              "        document.querySelector('#' + key + ' button');\n",
              "      quickchartButtonEl.disabled = true;  // To prevent multiple clicks.\n",
              "      quickchartButtonEl.classList.add('colab-df-spinner');\n",
              "      try {\n",
              "        const charts = await google.colab.kernel.invokeFunction(\n",
              "            'suggestCharts', [key], {});\n",
              "      } catch (error) {\n",
              "        console.error('Error during call to suggestCharts:', error);\n",
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              "      quickchartButtonEl.classList.remove('colab-df-spinner');\n",
              "      quickchartButtonEl.classList.add('colab-df-quickchart-complete');\n",
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              "\n",
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              "        box-shadow: 0px 1px 3px 1px rgba(0, 0, 0, 0.15);\n",
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              "    </style>\n",
              "    <button class=\"colab-df-generate\" onclick=\"generateWithVariable('df')\"\n",
              "            title=\"Generate code using this dataframe.\"\n",
              "            style=\"display:none;\">\n",
              "\n",
              "  <svg xmlns=\"http://www.w3.org/2000/svg\" height=\"24px\"viewBox=\"0 0 24 24\"\n",
              "       width=\"24px\">\n",
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              "    <script>\n",
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              "      buttonEl.style.display =\n",
              "        google.colab.kernel.accessAllowed ? 'block' : 'none';\n",
              "\n",
              "      buttonEl.onclick = () => {\n",
              "        google.colab.notebook.generateWithVariable('df');\n",
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              "\n",
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              "  </div>\n"
            ],
            "application/vnd.google.colaboratory.intrinsic+json": {
              "type": "dataframe",
              "variable_name": "df",
              "summary": "{\n  \"name\": \"df\",\n  \"rows\": 2469,\n  \"fields\": [\n    {\n      \"column\": \"Smiles\",\n      \"properties\": {\n        \"dtype\": \"string\",\n        \"num_unique_values\": 2469,\n        \"samples\": [\n          \"CCN1CCN(Cc2ccc(-c3cc4c(N[C@@H](C)c5ccccc5)ncnc4[nH]3)cc2)CC1\",\n          \"COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCC[C@H]1CC(N)=O\",\n          \"c1ccc(OCc2nnc(Cc3nc4ccccc4[nH]3)o2)cc1\"\n        ],\n        \"semantic_type\": \"\",\n        \"description\": \"\"\n      }\n    },\n    {\n      \"column\": \"pIC50\",\n      \"properties\": {\n        \"dtype\": \"number\",\n        \"std\": 1.4010867389571782,\n        \"min\": 1.602059991,\n        \"max\": 11.22184875,\n        \"num_unique_values\": 1231,\n        \"samples\": [\n          6.665546249,\n          5.665546249,\n          5.619788758\n        ],\n        \"semantic_type\": \"\",\n        \"description\": \"\"\n      }\n    }\n  ]\n}"
            }
          },
          "metadata": {},
          "execution_count": 4
        }
      ]
    },
    {
      "cell_type": "markdown",
      "source": [
        "#**FingerPrint & 2D Descriptors**"
      ],
      "metadata": {
        "id": "fNm5EtLXq6tP"
      }
    },
    {
      "cell_type": "code",
      "source": [
        "descriptors = []\n",
        "for i, row in df.iterrows():\n",
        "    m = Chem.MolFromSmiles(str(row[\"Smiles\"]))\n",
        "    desc = []\n",
        "\n",
        "    # calculate hashed atom pair fingerprint\n",
        "    fp = rdMolDescriptors.GetHashedAtomPairFingerprintAsBitVect(m)\n",
        "    desc.extend([int(x) for x in fp.ToBitString()])\n",
        "\n",
        "    # calculate RDK fingerprint\n",
        "    fp = Chem.RDKFingerprint(m)\n",
        "    desc.extend(fp)\n",
        "\n",
        "    # calculate additional molecular descriptors\n",
        "    desc.append(Descriptors.MolWt(m))\n",
        "    desc.append(Descriptors.MolLogP(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumHBA(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumHBD(m))\n",
        "    desc.append(Descriptors.TPSA(m))\n",
        "    desc.append(rdMolDescriptors.CalcFractionCSP3(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumRotatableBonds(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumAromaticRings(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumHeterocycles(m))\n",
        "\n",
        "    descriptors.append(desc)\n"
      ],
      "metadata": {
        "id": "ErQ2wGdGBXIF",
        "outputId": "e1cd2e2c-3a85-45f7-d403-275b5a3d10e9",
        "colab": {
          "base_uri": "https://localhost:8080/"
        }
      },
      "execution_count": 5,
      "outputs": [
        {
          "output_type": "stream",
          "name": "stderr",
          "text": [
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:55] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:56] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:57] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:58] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:37:59] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:00] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:01] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:02] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:03] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:04] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:05] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:06] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:07] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:08] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:09] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:10] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:11] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n",
            "[05:38:12] DEPRECATION WARNING: please use AtomPairGenerator\n"
          ]
        }
      ]
    },
    {
      "cell_type": "code",
      "source": [
        "# Convert the descriptors list to a Pandas dataframe\n",
        "df2 = pd.DataFrame(descriptors)\n",
        "df2.to_csv('decriptors.csv', index=False)\n",
        "df2"
      ],
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 424
        },
        "id": "t28RUVm9BeYI",
        "outputId": "e60355cd-efc9-4b57-885f-390b53a1c31f"
      },
      "execution_count": 6,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "      0     1     2     3     4     5     6     7     8     9     ...  4095  \\\n",
              "0        1     1     1     0     1     1     0     0     1     0  ...     0   \n",
              "1        0     0     0     0     1     0     0     0     0     0  ...     1   \n",
              "2        1     0     0     0     0     0     0     0     0     0  ...     1   \n",
              "3        0     0     0     0     0     0     0     0     0     0  ...     1   \n",
              "4        1     1     0     0     1     1     1     0     0     0  ...     1   \n",
              "...    ...   ...   ...   ...   ...   ...   ...   ...   ...   ...  ...   ...   \n",
              "2464     0     0     0     0     0     0     0     0     0     0  ...     0   \n",
              "2465     0     0     0     0     0     0     0     0     0     0  ...     0   \n",
              "2466     0     0     0     0     0     0     0     0     0     0  ...     0   \n",
              "2467     1     1     1     1     1     1     1     0     0     0  ...     0   \n",
              "2468     0     0     0     0     0     0     0     0     0     0  ...     0   \n",
              "\n",
              "         4096    4097  4098  4099    4100      4101  4102  4103  4104  \n",
              "0     440.463  4.0286     7     2  118.81  0.125000     7     5     2  \n",
              "1     337.810  4.5994     3     2   54.02  0.052632     5     3     1  \n",
              "2     235.290  3.2419     3     1   37.81  0.066667     3     3     1  \n",
              "3     427.291  5.0545     6     1   69.04  0.095238     4     4     2  \n",
              "4     303.362  2.3624     6     2   76.50  0.500000     4     2     1  \n",
              "...       ...     ...   ...   ...     ...       ...   ...   ...   ...  \n",
              "2464  281.315  3.3906     5     1   56.27  0.125000     4     3     1  \n",
              "2465  299.305  3.5297     5     1   56.27  0.125000     4     3     1  \n",
              "2466  360.211  4.1531     5     1   56.27  0.125000     4     3     1  \n",
              "2467  368.412  3.6308     6     1   73.06  0.350000     4     3     2  \n",
              "2468  373.412  5.1829     6     1   65.50  0.090909     6     4     1  \n",
              "\n",
              "[2469 rows x 4105 columns]"
            ],
            "text/html": [
              "\n",
              "  <div id=\"df-18faaf3a-55b6-4919-a542-3e39230cfc95\" class=\"colab-df-container\">\n",
              "    <div>\n",
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              "    .dataframe tbody tr th:only-of-type {\n",
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              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>0</th>\n",
              "      <th>1</th>\n",
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              "      <th>7</th>\n",
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              "      <th>...</th>\n",
              "      <th>4095</th>\n",
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              "      <th>4097</th>\n",
              "      <th>4098</th>\n",
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              "      <th>4102</th>\n",
              "      <th>4103</th>\n",
              "      <th>4104</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
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              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
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              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>440.463</td>\n",
              "      <td>4.0286</td>\n",
              "      <td>7</td>\n",
              "      <td>2</td>\n",
              "      <td>118.81</td>\n",
              "      <td>0.125000</td>\n",
              "      <td>7</td>\n",
              "      <td>5</td>\n",
              "      <td>2</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>1</td>\n",
              "      <td>337.810</td>\n",
              "      <td>4.5994</td>\n",
              "      <td>3</td>\n",
              "      <td>2</td>\n",
              "      <td>54.02</td>\n",
              "      <td>0.052632</td>\n",
              "      <td>5</td>\n",
              "      <td>3</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>1</td>\n",
              "      <td>235.290</td>\n",
              "      <td>3.2419</td>\n",
              "      <td>3</td>\n",
              "      <td>1</td>\n",
              "      <td>37.81</td>\n",
              "      <td>0.066667</td>\n",
              "      <td>3</td>\n",
              "      <td>3</td>\n",
              "      <td>1</td>\n",
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              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>1</td>\n",
              "      <td>427.291</td>\n",
              "      <td>5.0545</td>\n",
              "      <td>6</td>\n",
              "      <td>1</td>\n",
              "      <td>69.04</td>\n",
              "      <td>0.095238</td>\n",
              "      <td>4</td>\n",
              "      <td>4</td>\n",
              "      <td>2</td>\n",
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              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>1</td>\n",
              "      <td>303.362</td>\n",
              "      <td>2.3624</td>\n",
              "      <td>6</td>\n",
              "      <td>2</td>\n",
              "      <td>76.50</td>\n",
              "      <td>0.500000</td>\n",
              "      <td>4</td>\n",
              "      <td>2</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>...</th>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2464</th>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>281.315</td>\n",
              "      <td>3.3906</td>\n",
              "      <td>5</td>\n",
              "      <td>1</td>\n",
              "      <td>56.27</td>\n",
              "      <td>0.125000</td>\n",
              "      <td>4</td>\n",
              "      <td>3</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2465</th>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
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              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>299.305</td>\n",
              "      <td>3.5297</td>\n",
              "      <td>5</td>\n",
              "      <td>1</td>\n",
              "      <td>56.27</td>\n",
              "      <td>0.125000</td>\n",
              "      <td>4</td>\n",
              "      <td>3</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2466</th>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
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              "      <td>0</td>\n",
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              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>360.211</td>\n",
              "      <td>4.1531</td>\n",
              "      <td>5</td>\n",
              "      <td>1</td>\n",
              "      <td>56.27</td>\n",
              "      <td>0.125000</td>\n",
              "      <td>4</td>\n",
              "      <td>3</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2467</th>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>368.412</td>\n",
              "      <td>3.6308</td>\n",
              "      <td>6</td>\n",
              "      <td>1</td>\n",
              "      <td>73.06</td>\n",
              "      <td>0.350000</td>\n",
              "      <td>4</td>\n",
              "      <td>3</td>\n",
              "      <td>2</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2468</th>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>373.412</td>\n",
              "      <td>5.1829</td>\n",
              "      <td>6</td>\n",
              "      <td>1</td>\n",
              "      <td>65.50</td>\n",
              "      <td>0.090909</td>\n",
              "      <td>6</td>\n",
              "      <td>4</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>2469 rows × 4105 columns</p>\n",
              "</div>\n",
              "    <div class=\"colab-df-buttons\">\n",
              "\n",
              "  <div class=\"colab-df-container\">\n",
              "    <button class=\"colab-df-convert\" onclick=\"convertToInteractive('df-18faaf3a-55b6-4919-a542-3e39230cfc95')\"\n",
              "            title=\"Convert this dataframe to an interactive table.\"\n",
              "            style=\"display:none;\">\n",
              "\n",
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              "  </svg>\n",
              "    </button>\n",
              "\n",
              "  <style>\n",
              "    .colab-df-container {\n",
              "      display:flex;\n",
              "      gap: 12px;\n",
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              "\n",
              "    .colab-df-convert {\n",
              "      background-color: #E8F0FE;\n",
              "      border: none;\n",
              "      border-radius: 50%;\n",
              "      cursor: pointer;\n",
              "      display: none;\n",
              "      fill: #1967D2;\n",
              "      height: 32px;\n",
              "      padding: 0 0 0 0;\n",
              "      width: 32px;\n",
              "    }\n",
              "\n",
              "    .colab-df-convert:hover {\n",
              "      background-color: #E2EBFA;\n",
              "      box-shadow: 0px 1px 2px rgba(60, 64, 67, 0.3), 0px 1px 3px 1px rgba(60, 64, 67, 0.15);\n",
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              "\n",
              "    .colab-df-buttons div {\n",
              "      margin-bottom: 4px;\n",
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              "\n",
              "    [theme=dark] .colab-df-convert {\n",
              "      background-color: #3B4455;\n",
              "      fill: #D2E3FC;\n",
              "    }\n",
              "\n",
              "    [theme=dark] .colab-df-convert:hover {\n",
              "      background-color: #434B5C;\n",
              "      box-shadow: 0px 1px 3px 1px rgba(0, 0, 0, 0.15);\n",
              "      filter: drop-shadow(0px 1px 2px rgba(0, 0, 0, 0.3));\n",
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              "\n",
              "    <script>\n",
              "      const buttonEl =\n",
              "        document.querySelector('#df-18faaf3a-55b6-4919-a542-3e39230cfc95 button.colab-df-convert');\n",
              "      buttonEl.style.display =\n",
              "        google.colab.kernel.accessAllowed ? 'block' : 'none';\n",
              "\n",
              "      async function convertToInteractive(key) {\n",
              "        const element = document.querySelector('#df-18faaf3a-55b6-4919-a542-3e39230cfc95');\n",
              "        const dataTable =\n",
              "          await google.colab.kernel.invokeFunction('convertToInteractive',\n",
              "                                                    [key], {});\n",
              "        if (!dataTable) return;\n",
              "\n",
              "        const docLinkHtml = 'Like what you see? Visit the ' +\n",
              "          '<a target=\"_blank\" href=https://colab.research.google.com/notebooks/data_table.ipynb>data table notebook</a>'\n",
              "          + ' to learn more about interactive tables.';\n",
              "        element.innerHTML = '';\n",
              "        dataTable['output_type'] = 'display_data';\n",
              "        await google.colab.output.renderOutput(dataTable, element);\n",
              "        const docLink = document.createElement('div');\n",
              "        docLink.innerHTML = docLinkHtml;\n",
              "        element.appendChild(docLink);\n",
              "      }\n",
              "    </script>\n",
              "  </div>\n",
              "\n",
              "\n",
              "<div id=\"df-f102ae5b-6bed-4ea7-ab15-3ce6db744fd8\">\n",
              "  <button class=\"colab-df-quickchart\" onclick=\"quickchart('df-f102ae5b-6bed-4ea7-ab15-3ce6db744fd8')\"\n",
              "            title=\"Suggest charts\"\n",
              "            style=\"display:none;\">\n",
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              "<svg xmlns=\"http://www.w3.org/2000/svg\" height=\"24px\"viewBox=\"0 0 24 24\"\n",
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              "    </g>\n",
              "</svg>\n",
              "  </button>\n",
              "\n",
              "<style>\n",
              "  .colab-df-quickchart {\n",
              "      --bg-color: #E8F0FE;\n",
              "      --fill-color: #1967D2;\n",
              "      --hover-bg-color: #E2EBFA;\n",
              "      --hover-fill-color: #174EA6;\n",
              "      --disabled-fill-color: #AAA;\n",
              "      --disabled-bg-color: #DDD;\n",
              "  }\n",
              "\n",
              "  [theme=dark] .colab-df-quickchart {\n",
              "      --bg-color: #3B4455;\n",
              "      --fill-color: #D2E3FC;\n",
              "      --hover-bg-color: #434B5C;\n",
              "      --hover-fill-color: #FFFFFF;\n",
              "      --disabled-bg-color: #3B4455;\n",
              "      --disabled-fill-color: #666;\n",
              "  }\n",
              "\n",
              "  .colab-df-quickchart {\n",
              "    background-color: var(--bg-color);\n",
              "    border: none;\n",
              "    border-radius: 50%;\n",
              "    cursor: pointer;\n",
              "    display: none;\n",
              "    fill: var(--fill-color);\n",
              "    height: 32px;\n",
              "    padding: 0;\n",
              "    width: 32px;\n",
              "  }\n",
              "\n",
              "  .colab-df-quickchart:hover {\n",
              "    background-color: var(--hover-bg-color);\n",
              "    box-shadow: 0 1px 2px rgba(60, 64, 67, 0.3), 0 1px 3px 1px rgba(60, 64, 67, 0.15);\n",
              "    fill: var(--button-hover-fill-color);\n",
              "  }\n",
              "\n",
              "  .colab-df-quickchart-complete:disabled,\n",
              "  .colab-df-quickchart-complete:disabled:hover {\n",
              "    background-color: var(--disabled-bg-color);\n",
              "    fill: var(--disabled-fill-color);\n",
              "    box-shadow: none;\n",
              "  }\n",
              "\n",
              "  .colab-df-spinner {\n",
              "    border: 2px solid var(--fill-color);\n",
              "    border-color: transparent;\n",
              "    border-bottom-color: var(--fill-color);\n",
              "    animation:\n",
              "      spin 1s steps(1) infinite;\n",
              "  }\n",
              "\n",
              "  @keyframes spin {\n",
              "    0% {\n",
              "      border-color: transparent;\n",
              "      border-bottom-color: var(--fill-color);\n",
              "      border-left-color: var(--fill-color);\n",
              "    }\n",
              "    20% {\n",
              "      border-color: transparent;\n",
              "      border-left-color: var(--fill-color);\n",
              "      border-top-color: var(--fill-color);\n",
              "    }\n",
              "    30% {\n",
              "      border-color: transparent;\n",
              "      border-left-color: var(--fill-color);\n",
              "      border-top-color: var(--fill-color);\n",
              "      border-right-color: var(--fill-color);\n",
              "    }\n",
              "    40% {\n",
              "      border-color: transparent;\n",
              "      border-right-color: var(--fill-color);\n",
              "      border-top-color: var(--fill-color);\n",
              "    }\n",
              "    60% {\n",
              "      border-color: transparent;\n",
              "      border-right-color: var(--fill-color);\n",
              "    }\n",
              "    80% {\n",
              "      border-color: transparent;\n",
              "      border-right-color: var(--fill-color);\n",
              "      border-bottom-color: var(--fill-color);\n",
              "    }\n",
              "    90% {\n",
              "      border-color: transparent;\n",
              "      border-bottom-color: var(--fill-color);\n",
              "    }\n",
              "  }\n",
              "</style>\n",
              "\n",
              "  <script>\n",
              "    async function quickchart(key) {\n",
              "      const quickchartButtonEl =\n",
              "        document.querySelector('#' + key + ' button');\n",
              "      quickchartButtonEl.disabled = true;  // To prevent multiple clicks.\n",
              "      quickchartButtonEl.classList.add('colab-df-spinner');\n",
              "      try {\n",
              "        const charts = await google.colab.kernel.invokeFunction(\n",
              "            'suggestCharts', [key], {});\n",
              "      } catch (error) {\n",
              "        console.error('Error during call to suggestCharts:', error);\n",
              "      }\n",
              "      quickchartButtonEl.classList.remove('colab-df-spinner');\n",
              "      quickchartButtonEl.classList.add('colab-df-quickchart-complete');\n",
              "    }\n",
              "    (() => {\n",
              "      let quickchartButtonEl =\n",
              "        document.querySelector('#df-f102ae5b-6bed-4ea7-ab15-3ce6db744fd8 button');\n",
              "      quickchartButtonEl.style.display =\n",
              "        google.colab.kernel.accessAllowed ? 'block' : 'none';\n",
              "    })();\n",
              "  </script>\n",
              "</div>\n",
              "\n",
              "  <div id=\"id_8d2f1ee6-444e-4f13-8e09-4ebf33a546f0\">\n",
              "    <style>\n",
              "      .colab-df-generate {\n",
              "        background-color: #E8F0FE;\n",
              "        border: none;\n",
              "        border-radius: 50%;\n",
              "        cursor: pointer;\n",
              "        display: none;\n",
              "        fill: #1967D2;\n",
              "        height: 32px;\n",
              "        padding: 0 0 0 0;\n",
              "        width: 32px;\n",
              "      }\n",
              "\n",
              "      .colab-df-generate:hover {\n",
              "        background-color: #E2EBFA;\n",
              "        box-shadow: 0px 1px 2px rgba(60, 64, 67, 0.3), 0px 1px 3px 1px rgba(60, 64, 67, 0.15);\n",
              "        fill: #174EA6;\n",
              "      }\n",
              "\n",
              "      [theme=dark] .colab-df-generate {\n",
              "        background-color: #3B4455;\n",
              "        fill: #D2E3FC;\n",
              "      }\n",
              "\n",
              "      [theme=dark] .colab-df-generate:hover {\n",
              "        background-color: #434B5C;\n",
              "        box-shadow: 0px 1px 3px 1px rgba(0, 0, 0, 0.15);\n",
              "        filter: drop-shadow(0px 1px 2px rgba(0, 0, 0, 0.3));\n",
              "        fill: #FFFFFF;\n",
              "      }\n",
              "    </style>\n",
              "    <button class=\"colab-df-generate\" onclick=\"generateWithVariable('df2')\"\n",
              "            title=\"Generate code using this dataframe.\"\n",
              "            style=\"display:none;\">\n",
              "\n",
              "  <svg xmlns=\"http://www.w3.org/2000/svg\" height=\"24px\"viewBox=\"0 0 24 24\"\n",
              "       width=\"24px\">\n",
              "    <path d=\"M7,19H8.4L18.45,9,17,7.55,7,17.6ZM5,21V16.75L18.45,3.32a2,2,0,0,1,2.83,0l1.4,1.43a1.91,1.91,0,0,1,.58,1.4,1.91,1.91,0,0,1-.58,1.4L9.25,21ZM18.45,9,17,7.55Zm-12,3A5.31,5.31,0,0,0,4.9,8.1,5.31,5.31,0,0,0,1,6.5,5.31,5.31,0,0,0,4.9,4.9,5.31,5.31,0,0,0,6.5,1,5.31,5.31,0,0,0,8.1,4.9,5.31,5.31,0,0,0,12,6.5,5.46,5.46,0,0,0,6.5,12Z\"/>\n",
              "  </svg>\n",
              "    </button>\n",
              "    <script>\n",
              "      (() => {\n",
              "      const buttonEl =\n",
              "        document.querySelector('#id_8d2f1ee6-444e-4f13-8e09-4ebf33a546f0 button.colab-df-generate');\n",
              "      buttonEl.style.display =\n",
              "        google.colab.kernel.accessAllowed ? 'block' : 'none';\n",
              "\n",
              "      buttonEl.onclick = () => {\n",
              "        google.colab.notebook.generateWithVariable('df2');\n",
              "      }\n",
              "      })();\n",
              "    </script>\n",
              "  </div>\n",
              "\n",
              "    </div>\n",
              "  </div>\n"
            ],
            "application/vnd.google.colaboratory.intrinsic+json": {
              "type": "dataframe",
              "variable_name": "df2"
            }
          },
          "metadata": {},
          "execution_count": 6
        }
      ]
    },
    {
      "cell_type": "code",
      "source": [
        "X = df2\n",
        "y = df[\"pIC50\"]"
      ],
      "metadata": {
        "id": "X7OLkX8dB692"
      },
      "execution_count": 10,
      "outputs": []
    },
    {
      "cell_type": "markdown",
      "source": [
        "#**Split data into training and test sets**"
      ],
      "metadata": {
        "id": "MeevgZsdF82z"
      }
    },
    {
      "cell_type": "code",
      "execution_count": 11,
      "metadata": {
        "id": "vMnx3rK8ZTui"
      },
      "outputs": [],
      "source": [
        "\n",
        "X_train, X_test, y_train, y_test = train_test_split(X, y, test_size=0.20, random_state=42)\n"
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "Xz5safLBeuQu"
      },
      "source": [
        "# **QSAR Modell RandomForestRegressor**"
      ]
    },
    {
      "cell_type": "code",
      "execution_count": 12,
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 80
        },
        "id": "fmhzzkRtDg8h",
        "outputId": "2024f5dd-b702-43b6-d267-99c3d9bd0c82"
      },
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "RandomForestRegressor(random_state=42)"
            ],
            "text/html": [
              "<style>#sk-container-id-1 {\n",
              "  /* Definition of color scheme common for light and dark mode */\n",
              "  --sklearn-color-text: #000;\n",
              "  --sklearn-color-text-muted: #666;\n",
              "  --sklearn-color-line: gray;\n",
              "  /* Definition of color scheme for unfitted estimators */\n",
              "  --sklearn-color-unfitted-level-0: #fff5e6;\n",
              "  --sklearn-color-unfitted-level-1: #f6e4d2;\n",
              "  --sklearn-color-unfitted-level-2: #ffe0b3;\n",
              "  --sklearn-color-unfitted-level-3: chocolate;\n",
              "  /* Definition of color scheme for fitted estimators */\n",
              "  --sklearn-color-fitted-level-0: #f0f8ff;\n",
              "  --sklearn-color-fitted-level-1: #d4ebff;\n",
              "  --sklearn-color-fitted-level-2: #b3dbfd;\n",
              "  --sklearn-color-fitted-level-3: cornflowerblue;\n",
              "\n",
              "  /* Specific color for light theme */\n",
              "  --sklearn-color-text-on-default-background: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, black)));\n",
              "  --sklearn-color-background: var(--sg-background-color, var(--theme-background, var(--jp-layout-color0, white)));\n",
              "  --sklearn-color-border-box: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, black)));\n",
              "  --sklearn-color-icon: #696969;\n",
              "\n",
              "  @media (prefers-color-scheme: dark) {\n",
              "    /* Redefinition of color scheme for dark theme */\n",
              "    --sklearn-color-text-on-default-background: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, white)));\n",
              "    --sklearn-color-background: var(--sg-background-color, var(--theme-background, var(--jp-layout-color0, #111)));\n",
              "    --sklearn-color-border-box: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, white)));\n",
              "    --sklearn-color-icon: #878787;\n",
              "  }\n",
              "}\n",
              "\n",
              "#sk-container-id-1 {\n",
              "  color: var(--sklearn-color-text);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 pre {\n",
              "  padding: 0;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 input.sk-hidden--visually {\n",
              "  border: 0;\n",
              "  clip: rect(1px 1px 1px 1px);\n",
              "  clip: rect(1px, 1px, 1px, 1px);\n",
              "  height: 1px;\n",
              "  margin: -1px;\n",
              "  overflow: hidden;\n",
              "  padding: 0;\n",
              "  position: absolute;\n",
              "  width: 1px;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-dashed-wrapped {\n",
              "  border: 1px dashed var(--sklearn-color-line);\n",
              "  margin: 0 0.4em 0.5em 0.4em;\n",
              "  box-sizing: border-box;\n",
              "  padding-bottom: 0.4em;\n",
              "  background-color: var(--sklearn-color-background);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-container {\n",
              "  /* jupyter's `normalize.less` sets `[hidden] { display: none; }`\n",
              "     but bootstrap.min.css set `[hidden] { display: none !important; }`\n",
              "     so we also need the `!important` here to be able to override the\n",
              "     default hidden behavior on the sphinx rendered scikit-learn.org.\n",
              "     See: https://github.com/scikit-learn/scikit-learn/issues/21755 */\n",
              "  display: inline-block !important;\n",
              "  position: relative;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-text-repr-fallback {\n",
              "  display: none;\n",
              "}\n",
              "\n",
              "div.sk-parallel-item,\n",
              "div.sk-serial,\n",
              "div.sk-item {\n",
              "  /* draw centered vertical line to link estimators */\n",
              "  background-image: linear-gradient(var(--sklearn-color-text-on-default-background), var(--sklearn-color-text-on-default-background));\n",
              "  background-size: 2px 100%;\n",
              "  background-repeat: no-repeat;\n",
              "  background-position: center center;\n",
              "}\n",
              "\n",
              "/* Parallel-specific style estimator block */\n",
              "\n",
              "#sk-container-id-1 div.sk-parallel-item::after {\n",
              "  content: \"\";\n",
              "  width: 100%;\n",
              "  border-bottom: 2px solid var(--sklearn-color-text-on-default-background);\n",
              "  flex-grow: 1;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-parallel {\n",
              "  display: flex;\n",
              "  align-items: stretch;\n",
              "  justify-content: center;\n",
              "  background-color: var(--sklearn-color-background);\n",
              "  position: relative;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-parallel-item {\n",
              "  display: flex;\n",
              "  flex-direction: column;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-parallel-item:first-child::after {\n",
              "  align-self: flex-end;\n",
              "  width: 50%;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-parallel-item:last-child::after {\n",
              "  align-self: flex-start;\n",
              "  width: 50%;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-parallel-item:only-child::after {\n",
              "  width: 0;\n",
              "}\n",
              "\n",
              "/* Serial-specific style estimator block */\n",
              "\n",
              "#sk-container-id-1 div.sk-serial {\n",
              "  display: flex;\n",
              "  flex-direction: column;\n",
              "  align-items: center;\n",
              "  background-color: var(--sklearn-color-background);\n",
              "  padding-right: 1em;\n",
              "  padding-left: 1em;\n",
              "}\n",
              "\n",
              "\n",
              "/* Toggleable style: style used for estimator/Pipeline/ColumnTransformer box that is\n",
              "clickable and can be expanded/collapsed.\n",
              "- Pipeline and ColumnTransformer use this feature and define the default style\n",
              "- Estimators will overwrite some part of the style using the `sk-estimator` class\n",
              "*/\n",
              "\n",
              "/* Pipeline and ColumnTransformer style (default) */\n",
              "\n",
              "#sk-container-id-1 div.sk-toggleable {\n",
              "  /* Default theme specific background. It is overwritten whether we have a\n",
              "  specific estimator or a Pipeline/ColumnTransformer */\n",
              "  background-color: var(--sklearn-color-background);\n",
              "}\n",
              "\n",
              "/* Toggleable label */\n",
              "#sk-container-id-1 label.sk-toggleable__label {\n",
              "  cursor: pointer;\n",
              "  display: flex;\n",
              "  width: 100%;\n",
              "  margin-bottom: 0;\n",
              "  padding: 0.5em;\n",
              "  box-sizing: border-box;\n",
              "  text-align: center;\n",
              "  align-items: start;\n",
              "  justify-content: space-between;\n",
              "  gap: 0.5em;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 label.sk-toggleable__label .caption {\n",
              "  font-size: 0.6rem;\n",
              "  font-weight: lighter;\n",
              "  color: var(--sklearn-color-text-muted);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 label.sk-toggleable__label-arrow:before {\n",
              "  /* Arrow on the left of the label */\n",
              "  content: \"▸\";\n",
              "  float: left;\n",
              "  margin-right: 0.25em;\n",
              "  color: var(--sklearn-color-icon);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 label.sk-toggleable__label-arrow:hover:before {\n",
              "  color: var(--sklearn-color-text);\n",
              "}\n",
              "\n",
              "/* Toggleable content - dropdown */\n",
              "\n",
              "#sk-container-id-1 div.sk-toggleable__content {\n",
              "  max-height: 0;\n",
              "  max-width: 0;\n",
              "  overflow: hidden;\n",
              "  text-align: left;\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-0);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-toggleable__content.fitted {\n",
              "  /* fitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-0);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-toggleable__content pre {\n",
              "  margin: 0.2em;\n",
              "  border-radius: 0.25em;\n",
              "  color: var(--sklearn-color-text);\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-0);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-toggleable__content.fitted pre {\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-0);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 input.sk-toggleable__control:checked~div.sk-toggleable__content {\n",
              "  /* Expand drop-down */\n",
              "  max-height: 200px;\n",
              "  max-width: 100%;\n",
              "  overflow: auto;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 input.sk-toggleable__control:checked~label.sk-toggleable__label-arrow:before {\n",
              "  content: \"▾\";\n",
              "}\n",
              "\n",
              "/* Pipeline/ColumnTransformer-specific style */\n",
              "\n",
              "#sk-container-id-1 div.sk-label input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
              "  color: var(--sklearn-color-text);\n",
              "  background-color: var(--sklearn-color-unfitted-level-2);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-label.fitted input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
              "  background-color: var(--sklearn-color-fitted-level-2);\n",
              "}\n",
              "\n",
              "/* Estimator-specific style */\n",
              "\n",
              "/* Colorize estimator box */\n",
              "#sk-container-id-1 div.sk-estimator input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-2);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-estimator.fitted input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
              "  /* fitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-2);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-label label.sk-toggleable__label,\n",
              "#sk-container-id-1 div.sk-label label {\n",
              "  /* The background is the default theme color */\n",
              "  color: var(--sklearn-color-text-on-default-background);\n",
              "}\n",
              "\n",
              "/* On hover, darken the color of the background */\n",
              "#sk-container-id-1 div.sk-label:hover label.sk-toggleable__label {\n",
              "  color: var(--sklearn-color-text);\n",
              "  background-color: var(--sklearn-color-unfitted-level-2);\n",
              "}\n",
              "\n",
              "/* Label box, darken color on hover, fitted */\n",
              "#sk-container-id-1 div.sk-label.fitted:hover label.sk-toggleable__label.fitted {\n",
              "  color: var(--sklearn-color-text);\n",
              "  background-color: var(--sklearn-color-fitted-level-2);\n",
              "}\n",
              "\n",
              "/* Estimator label */\n",
              "\n",
              "#sk-container-id-1 div.sk-label label {\n",
              "  font-family: monospace;\n",
              "  font-weight: bold;\n",
              "  display: inline-block;\n",
              "  line-height: 1.2em;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-label-container {\n",
              "  text-align: center;\n",
              "}\n",
              "\n",
              "/* Estimator-specific */\n",
              "#sk-container-id-1 div.sk-estimator {\n",
              "  font-family: monospace;\n",
              "  border: 1px dotted var(--sklearn-color-border-box);\n",
              "  border-radius: 0.25em;\n",
              "  box-sizing: border-box;\n",
              "  margin-bottom: 0.5em;\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-0);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-estimator.fitted {\n",
              "  /* fitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-0);\n",
              "}\n",
              "\n",
              "/* on hover */\n",
              "#sk-container-id-1 div.sk-estimator:hover {\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-2);\n",
              "}\n",
              "\n",
              "#sk-container-id-1 div.sk-estimator.fitted:hover {\n",
              "  /* fitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-2);\n",
              "}\n",
              "\n",
              "/* Specification for estimator info (e.g. \"i\" and \"?\") */\n",
              "\n",
              "/* Common style for \"i\" and \"?\" */\n",
              "\n",
              ".sk-estimator-doc-link,\n",
              "a:link.sk-estimator-doc-link,\n",
              "a:visited.sk-estimator-doc-link {\n",
              "  float: right;\n",
              "  font-size: smaller;\n",
              "  line-height: 1em;\n",
              "  font-family: monospace;\n",
              "  background-color: var(--sklearn-color-background);\n",
              "  border-radius: 1em;\n",
              "  height: 1em;\n",
              "  width: 1em;\n",
              "  text-decoration: none !important;\n",
              "  margin-left: 0.5em;\n",
              "  text-align: center;\n",
              "  /* unfitted */\n",
              "  border: var(--sklearn-color-unfitted-level-1) 1pt solid;\n",
              "  color: var(--sklearn-color-unfitted-level-1);\n",
              "}\n",
              "\n",
              ".sk-estimator-doc-link.fitted,\n",
              "a:link.sk-estimator-doc-link.fitted,\n",
              "a:visited.sk-estimator-doc-link.fitted {\n",
              "  /* fitted */\n",
              "  border: var(--sklearn-color-fitted-level-1) 1pt solid;\n",
              "  color: var(--sklearn-color-fitted-level-1);\n",
              "}\n",
              "\n",
              "/* On hover */\n",
              "div.sk-estimator:hover .sk-estimator-doc-link:hover,\n",
              ".sk-estimator-doc-link:hover,\n",
              "div.sk-label-container:hover .sk-estimator-doc-link:hover,\n",
              ".sk-estimator-doc-link:hover {\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-3);\n",
              "  color: var(--sklearn-color-background);\n",
              "  text-decoration: none;\n",
              "}\n",
              "\n",
              "div.sk-estimator.fitted:hover .sk-estimator-doc-link.fitted:hover,\n",
              ".sk-estimator-doc-link.fitted:hover,\n",
              "div.sk-label-container:hover .sk-estimator-doc-link.fitted:hover,\n",
              ".sk-estimator-doc-link.fitted:hover {\n",
              "  /* fitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-3);\n",
              "  color: var(--sklearn-color-background);\n",
              "  text-decoration: none;\n",
              "}\n",
              "\n",
              "/* Span, style for the box shown on hovering the info icon */\n",
              ".sk-estimator-doc-link span {\n",
              "  display: none;\n",
              "  z-index: 9999;\n",
              "  position: relative;\n",
              "  font-weight: normal;\n",
              "  right: .2ex;\n",
              "  padding: .5ex;\n",
              "  margin: .5ex;\n",
              "  width: min-content;\n",
              "  min-width: 20ex;\n",
              "  max-width: 50ex;\n",
              "  color: var(--sklearn-color-text);\n",
              "  box-shadow: 2pt 2pt 4pt #999;\n",
              "  /* unfitted */\n",
              "  background: var(--sklearn-color-unfitted-level-0);\n",
              "  border: .5pt solid var(--sklearn-color-unfitted-level-3);\n",
              "}\n",
              "\n",
              ".sk-estimator-doc-link.fitted span {\n",
              "  /* fitted */\n",
              "  background: var(--sklearn-color-fitted-level-0);\n",
              "  border: var(--sklearn-color-fitted-level-3);\n",
              "}\n",
              "\n",
              ".sk-estimator-doc-link:hover span {\n",
              "  display: block;\n",
              "}\n",
              "\n",
              "/* \"?\"-specific style due to the `<a>` HTML tag */\n",
              "\n",
              "#sk-container-id-1 a.estimator_doc_link {\n",
              "  float: right;\n",
              "  font-size: 1rem;\n",
              "  line-height: 1em;\n",
              "  font-family: monospace;\n",
              "  background-color: var(--sklearn-color-background);\n",
              "  border-radius: 1rem;\n",
              "  height: 1rem;\n",
              "  width: 1rem;\n",
              "  text-decoration: none;\n",
              "  /* unfitted */\n",
              "  color: var(--sklearn-color-unfitted-level-1);\n",
              "  border: var(--sklearn-color-unfitted-level-1) 1pt solid;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 a.estimator_doc_link.fitted {\n",
              "  /* fitted */\n",
              "  border: var(--sklearn-color-fitted-level-1) 1pt solid;\n",
              "  color: var(--sklearn-color-fitted-level-1);\n",
              "}\n",
              "\n",
              "/* On hover */\n",
              "#sk-container-id-1 a.estimator_doc_link:hover {\n",
              "  /* unfitted */\n",
              "  background-color: var(--sklearn-color-unfitted-level-3);\n",
              "  color: var(--sklearn-color-background);\n",
              "  text-decoration: none;\n",
              "}\n",
              "\n",
              "#sk-container-id-1 a.estimator_doc_link.fitted:hover {\n",
              "  /* fitted */\n",
              "  background-color: var(--sklearn-color-fitted-level-3);\n",
              "}\n",
              "</style><div id=\"sk-container-id-1\" class=\"sk-top-container\"><div class=\"sk-text-repr-fallback\"><pre>RandomForestRegressor(random_state=42)</pre><b>In a Jupyter environment, please rerun this cell to show the HTML representation or trust the notebook. <br />On GitHub, the HTML representation is unable to render, please try loading this page with nbviewer.org.</b></div><div class=\"sk-container\" hidden><div class=\"sk-item\"><div class=\"sk-estimator fitted sk-toggleable\"><input class=\"sk-toggleable__control sk-hidden--visually\" id=\"sk-estimator-id-1\" type=\"checkbox\" checked><label for=\"sk-estimator-id-1\" class=\"sk-toggleable__label fitted sk-toggleable__label-arrow\"><div><div>RandomForestRegressor</div></div><div><a class=\"sk-estimator-doc-link fitted\" rel=\"noreferrer\" target=\"_blank\" href=\"https://scikit-learn.org/1.6/modules/generated/sklearn.ensemble.RandomForestRegressor.html\">?<span>Documentation for RandomForestRegressor</span></a><span class=\"sk-estimator-doc-link fitted\">i<span>Fitted</span></span></div></label><div class=\"sk-toggleable__content fitted\"><pre>RandomForestRegressor(random_state=42)</pre></div> </div></div></div></div>"
            ]
          },
          "metadata": {},
          "execution_count": 12
        }
      ],
      "source": [
        "# train QSAR model\n",
        "model = RandomForestRegressor(random_state=42)\n",
        "model.fit(X, y)"
      ]
    },
    {
      "cell_type": "code",
      "execution_count": 13,
      "metadata": {
        "id": "ng_u1LU_DlfJ"
      },
      "outputs": [],
      "source": [
        "# predict bioactivity on test set\n",
        "y_pred = model.predict(X)"
      ]
    },
    {
      "cell_type": "code",
      "execution_count": 14,
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "8dnObJB7DpF6",
        "outputId": "86894aee-38f5-4795-98bb-d91945f25cd5"
      },
      "outputs": [
        {
          "output_type": "stream",
          "name": "stdout",
          "text": [
            "R^2: 0.9489283858045139\n"
          ]
        }
      ],
      "source": [
        "# evaluate model performance\n",
        "print(\"R^2:\", model.score(X_test, y_test))"
      ]
    },
    {
      "cell_type": "code",
      "execution_count": 15,
      "metadata": {
        "id": "GN0eLD8JNgKL"
      },
      "outputs": [],
      "source": [
        "import matplotlib.pyplot as plt\n",
        "import numpy as np"
      ]
    },
    {
      "cell_type": "code",
      "execution_count": 16,
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 465
        },
        "id": "ngLnAqYKNiNa",
        "outputId": "34a5baf6-ea22-4b7a-e736-197d17ea7e86"
      },
      "outputs": [
        {
          "output_type": "display_data",
          "data": {
            "text/plain": [
              "<Figure size 500x500 with 1 Axes>"
            ],
            "image/png": 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\n"
          },
          "metadata": {}
        }
      ],
      "source": [
        "plt.figure(figsize=(5,5))\n",
        "plt.scatter(x=y, y=y_pred, c=\"#7CAE00\", alpha=0.3)\n",
        "\n",
        "z = np.polyfit(y, y_pred, 1)\n",
        "p = np.poly1d(z)\n",
        "\n",
        "plt.plot(y,p(y),\"#F8766D\")\n",
        "plt.ylabel('Predicted pIC50')\n",
        "plt.xlabel('Experimental pIC50')\n",
        "plt.savefig('regression_curve.pdf')"
      ]
    },
    {
      "cell_type": "markdown",
      "source": [
        "#**Define a function to calculate the descriptors of a new molecule and Predict pIC50**"
      ],
      "metadata": {
        "id": "Pqk9p0_5YjPi"
      }
    },
    {
      "cell_type": "code",
      "execution_count": null,
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "5oLvbSEADylZ",
        "outputId": "0bce537a-8b27-4028-bac0-88aa68bac060"
      },
      "outputs": [
        {
          "output_type": "stream",
          "name": "stdout",
          "text": [
            "Predicted bioactivity: [8.31563077]\n"
          ]
        }
      ],
      "source": [
        "def predict_bioactivity(smiles):\n",
        "    m = Chem.MolFromSmiles(smiles)\n",
        "    desc = []\n",
        "\n",
        "    # calculate hashed atom pair fingerprint\n",
        "    fp = rdMolDescriptors.GetHashedAtomPairFingerprintAsBitVect(m)\n",
        "    desc.extend([int(x) for x in fp.ToBitString()])\n",
        "\n",
        "    # calculate RDK fingerprint\n",
        "    fp = Chem.RDKFingerprint(m)\n",
        "    desc.extend(fp)\n",
        "\n",
        "    # calculate additional molecular descriptors\n",
        "    desc.append(Descriptors.MolWt(m))\n",
        "    desc.append(Descriptors.MolLogP(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumHBA(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumHBD(m))\n",
        "    desc.append(Descriptors.TPSA(m))\n",
        "    desc.append(rdMolDescriptors.CalcFractionCSP3(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumRotatableBonds(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumAromaticRings(m))\n",
        "    desc.append(rdMolDescriptors.CalcNumHeterocycles(m))\n",
        "\n",
        "    descriptors.append(desc)\n",
        "    return desc\n",
        "\n",
        "# predict bioactivity of new molecule (Campesterol)\n",
        "smiles = \"CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3\"\n",
        "X_new = np.array(predict_bioactivity(smiles)).reshape(1, -1)\n",
        "\n",
        "# Print the selected features\n",
        "#print(selected_features)\n",
        "bioactivity = model.predict(X_new)\n",
        "print(\"Predicted bioactivity:\", bioactivity)"
      ]
    },
    {
      "cell_type": "markdown",
      "source": [
        "#**Convert pIC50 to IC50 (nm)**"
      ],
      "metadata": {
        "id": "jBLq3xGOZABJ"
      }
    },
    {
      "cell_type": "code",
      "source": [
        "pIC50 = bioactivity\n",
        "IC50 = (10**-pIC50)*(10**9)\n",
        "print(\"IC50:\", IC50, \"nM\")"
      ],
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "uPw3Tfv9QEpM",
        "outputId": "eccc0876-09cb-4eda-dc4e-a80232094905"
      },
      "execution_count": null,
      "outputs": [
        {
          "output_type": "stream",
          "name": "stdout",
          "text": [
            "IC50: [4.83469669] nM\n"
          ]
        }
      ]
    },
    {
      "cell_type": "markdown",
      "source": [
        "# **QSAR Model Artificial Neural Network**"
      ],
      "metadata": {
        "id": "78JdA94GCoTn"
      }
    },
    {
      "cell_type": "code",
      "source": [
        "from sklearn.neural_network import MLPRegressor\n",
        "from sklearn.model_selection import train_test_split\n",
        "from sklearn.preprocessing import StandardScaler\n",
        "\n",
        "# Preprocess data\n",
        "scaler = StandardScaler()\n",
        "X_scaled = scaler.fit_transform(X)\n",
        "\n",
        "# Split the data into training and testing sets\n",
        "X_train, X_test, y_train, y_test = train_test_split(X_scaled, y, test_size=0.2, random_state=42)\n",
        "\n",
        "# Train the ANN model\n",
        "model = MLPRegressor(hidden_layer_sizes=(100, 50),  # Example: Two layers with 100 and 50 neurons\n",
        "                     activation='relu',            # Activation function\n",
        "                     solver='adam',                # Optimization algorithm\n",
        "                     max_iter=1000,                # Maximum number of iterations\n",
        "                     random_state=42)\n",
        "model.fit(X_train, y_train)\n",
        "\n",
        "# Evaluate the model\n",
        "score = model.score(X_test, y_test)\n",
        "print(\"ANN Model R^2 Score:\", score)\n"
      ],
      "metadata": {
        "id": "-kfoAVivEsg4",
        "outputId": "6cac7bbc-292b-4438-d18b-7577be71e67b",
        "colab": {
          "base_uri": "https://localhost:8080/"
        }
      },
      "execution_count": 8,
      "outputs": [
        {
          "output_type": "stream",
          "name": "stdout",
          "text": [
            "ANN Model R^2 Score: 0.4847909705454202\n"
          ]
        }
      ]
    },
    {
      "cell_type": "markdown",
      "source": [
        "# **Support Vector Machine**"
      ],
      "metadata": {
        "id": "sbyFQZDXE7qb"
      }
    },
    {
      "cell_type": "code",
      "source": [
        "from sklearn.svm import SVR\n",
        "from sklearn.model_selection import train_test_split\n",
        "from sklearn.preprocessing import StandardScaler\n",
        "\n",
        "# Preprocess data\n",
        "scaler = StandardScaler()\n",
        "X_scaled = scaler.fit_transform(X)\n",
        "\n",
        "# Split the data into training and testing sets\n",
        "X_train, X_test, y_train, y_test = train_test_split(X_scaled, y, test_size=0.2, random_state=42)\n",
        "\n",
        "# Train the SVM model\n",
        "model = SVR(kernel='rbf', C=1.0, epsilon=0.1)  # Radial basis function kernel\n",
        "model.fit(X_train, y_train)\n",
        "\n",
        "# Evaluate the model\n",
        "score = model.score(X_test, y_test)\n",
        "print(\"SVM Model R^2 Score:\", score)\n"
      ],
      "metadata": {
        "id": "3P6Rldv3FEBD",
        "outputId": "bb52244a-0602-4401-f154-c480019e1475",
        "colab": {
          "base_uri": "https://localhost:8080/"
        }
      },
      "execution_count": 9,
      "outputs": [
        {
          "output_type": "stream",
          "name": "stdout",
          "text": [
            "SVM Model R^2 Score: 0.6692917866087185\n"
          ]
        }
      ]
    }
  ]
}