diff --git a/applications/jupyterlab/Dockerfile b/applications/jupyterlab/Dockerfile
index 151473ad..ecf6a4e4 100644
--- a/applications/jupyterlab/Dockerfile
+++ b/applications/jupyterlab/Dockerfile
@@ -31,7 +31,6 @@ RUN pip install -r requirements.txt --upgrade --no-cache-dir
 RUN jupyter labextension install plotlywidget
 
 
-
 ##############
 
 USER root
@@ -44,6 +43,10 @@ RUN echo -e '#!/bin/bash\n#Reusing the jNeuroML jar from the pip installed pyNeu
 RUN chmod +x /opt/conda/bin/jnml
 ENV JNML_HOME=/opt/conda/bin
 
+### Set up lems, reusing pynml jar
+RUN echo -e '#!/bin/bash\n#Reusing the jNeuroML jar from the pip installed pyNeuroML for the lems command\n\njava -classpath /opt/conda/lib/python3.9/site-packages/pyneuroml/lib/jNeuroML-*-jar-with-dependencies.jar org.lemsml.jlems.viz.VizMain $@' >> /opt/conda/bin/lems
+RUN chmod +x /opt/conda/bin/lems
+
 RUN cat ~/.bashrc
 
 
@@ -84,13 +87,34 @@ RUN apt-get update && apt-get install libopenmpi-dev -y
 #  Octave etc.
 RUN apt-get update && apt-get install octave octave-statistics -y
 
+#  NEST 
+ENV NEST_VER=3.5
+ENV NEST_HOME=/opt/conda/nest
+RUN cd /tmp && \
+    wget -nv https://github.com/nest/nest-simulator/archive/v$NEST_VER.tar.gz && \
+    tar xvzf v$NEST_VER.tar.gz && \
+    mv nest-simulator-$NEST_VER nest && \
+    cd nest && \
+    mkdir $NEST_HOME && \
+    apt-get install libgsl-dev -y && \
+    cmake -DCMAKE_INSTALL_PREFIX:PATH=$NEST_HOME -DPYTHON_EXECUTABLE:FILEPATH=/opt/conda/bin/python -DPYTHON_INCLUDE_DIR=/opt/conda/include/python3.9 . && \
+    make -j7 && \
+    make install
+ENV PYTHONPATH=$NEST_HOME/lib/python3.9/site-packages
+ENV PATH=$PATH:$NEST_HOME/bin
+
 USER jovyan
 #### Install Python packages
 RUN pip install -r requirements.txt --upgrade --no-cache-dir
 
+#  Compile NEURON mod files for PyNN
+RUN cd /opt/conda/lib/python3.9/site-packages/pyNN/neuron/nmodl && nrnivmodl
+# See https://github.com/OpenSourceBrain/osb-model-validation/issues/91 for status of this
+RUN pip install 'numpy<=1.23.0' # temp fix for https://levelup.gitconnected.com/fix-attributeerror-module-numpy-has-no-attribute-float-d7d68c5a4971
+
 #########################################################################
 # fix for https://github.com/jupyter/notebook/issues/7048
-
 RUN pip install traitlets==5.9.0
+
 COPY --chown=jovyan:users overrides/* /opt/conda/share/jupyter/lab/static/
 WORKDIR /opt/workspace
diff --git a/applications/jupyterlab/requirements.txt b/applications/jupyterlab/requirements.txt
index 20718921..9f0bb0c5 100644
--- a/applications/jupyterlab/requirements.txt
+++ b/applications/jupyterlab/requirements.txt
@@ -57,8 +57,18 @@ tvb-data
 ipympl
 
 
+####  SBML/COMBINE packages
+python-libsbml
+tellurium
+
+
 ####  General Python packages
 plotly
 
+
+#### Install OMV
+git+https://github.com/OpenSourceBrain/osb-model-validation.git@v0.2.15
+
+
 ####  Final updates
 numpy  # Removes some issues with LFPy...
\ No newline at end of file