diff --git a/requirements.txt b/requirements.txt
index 261996a..044e8d4 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,7 +1,7 @@
 setuptools
 numpy>=1.20.0
 pandas>=2.2
-mdanalysis>=2.0.0
+mdanalysis>=2.7.0
 pytest
 pathlib
 matplotlib
diff --git a/setup.py b/setup.py
index b59b9cb..0cf0fa8 100644
--- a/setup.py
+++ b/setup.py
@@ -46,7 +46,7 @@
         "mdanalysis>=2.7.0",
         "pandas",
         "matplotlib",
-        "scipy==0.12.0",
+        "scipy==1.12.0",
         "statsmodels",
         "plotly",
         "rdkit",