get the float copy number values

[hushuzuiniu]

Hi

I have been utilizing your tool for CNV analysis and have found it to be exceptionally useful. However, I have encountered an issue where the copy number values derived from the _ratio.txt files are integers. I am interested in obtaining these values as floating-point numbers for more precise analysis. Could you please guide me on how to modify the settings or process to achieve this?

Additionally, I would like to know if it is possible to calculate tumor purity using this tool.

Thank you for your assistance.

Shu

[valeu]

Dear Shu, the new version that can reliably calculate the tumor purity should be available by the end of August.

For floats, just multiply the median ratio by ploidy.

[hushuzuiniu]

Dear Valeu,

Thank you for your assistance.

I look forward to the updated version of the tool, as it will be of great help. I also have a question regarding the use of floats: should the median ratio be multiplied by a constant ploidy value? Specifically, for human samples, should the median ratio always be multiplied by 2?

Best regards,
Shu